Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3Tyr705 phosphorylation
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3510
Abstract: Aberrant signal transducer and activator of transcription 3 (STAT3) signaling promotes the initiation and progression of cancer in humans by either inhibiting apoptosis or inducing cell proliferation, angiogenesis, invasion, and metastasis. The role of resveratrol（RES）in… read more here.
Keywords: resveratrol; cervical cancer; potential cervical; cancer ... See more keywords
Pro‐inflammatory M1 macrophage enhances metastatic potential of ovarian cancer cells through NF‐κB activation
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22750
Abstract: Obesity is a serious health problem and critically related to poor prognosis in cancer, presumably through induction of chronic inflammation. The major culprit for cancer progression in obesity is presumed to be macrophages. Accumulation of… read more here.
Keywords: treatment; ovarian cancer; macrophage; cancer cells ... See more keywords
Dichloromethane increases mutagenic DNA damage and transformation ability in cholangiocytes and enhances metastatic potential in cholangiocarcinoma cell lines.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109580
Abstract: Dichloromethane (DCM), a widely used chlorinated solvent, is classified by IARC (2017) as probably carcinogenic to humans. Exposure to DCM has been associated with increased incidence of cholangiocarcinoma (CCA) in humans. This study aimed to… read more here.
Keywords: dna damage; mutagenic dna; cell lines; transformation ... See more keywords
Metabolic reprogramming underlies metastatic potential in an obesity-responsive murine model of metastatic triple negative breast cancer
Sign Up to like & getrecommendations! Published in 2017 at "NPJ Breast Cancer"
DOI: 10.1038/s41523-017-0027-5
Abstract: The vast majority of cancer-related deaths are due to metastatic disease, whereby primary tumor cells disseminate and colonize distal sites within the body. Triple negative breast cancer typically displays aberrant Wnt signaling, lacks effective targeted… read more here.
Keywords: negative breast; breast cancer; cancer; metastatic potential ... See more keywords
Ethanol extract of loquat fruit skin inhibits the proliferation and metastatic potential of EJ human bladder carcinoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2017.1358665
Abstract: ABSTRACT Although studies on biological properties of loquat plant have been performed, research on the molecular mechanism of action in loquat fruit skin is very limited. Therefore, we investigated the molecular mechanisms underlying the inhibitory… read more here.
Keywords: fruit skin; metastatic potential; loquat fruit; proliferation ... See more keywords
Quantitative Biophysical Metrics for Rapid Evaluation of Ovarian Cancer Metastatic Potential.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e21-08-0419
Abstract: Ovarian cancer is routinely diagnosed long after the disease has metastasized through the fibrous sub-mesothelium. Despite extensive research in the field linking ovarian cancer progression to increasingly poor prognosis, there are currently no validated cellular… read more here.
Keywords: ovarian cancer; metastatic potential; media see; see text ... See more keywords
Flavonoids from ethanol extracts of euphorbia hirta inhibit melanoma growth and metastatic potential
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz429.008
Abstract: Abstract Background Euphorbia hirta has many health benefits for enhancing human health. It exhibits various antioxidant properties. Our aim was to investigate the effects of several polyphenols from Euphorbia hirta ethanolic extract on the growth… read more here.
Keywords: melanoma; b16f10; growth metastatic; euphorbia hirta ... See more keywords
The metastatic potential of seminomatous germ cell tumours is associated with a specific microRNA pattern
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DOI: 10.1111/andr.12838
Abstract: Seminomatous germ cell tumours (SGCT) are the most frequent malignancy in young men. Reliable prognostic biomarkers for the prediction of metastasis at diagnosis and the risk of relapse in clinical stage I (CSI) are lacking.… read more here.
Keywords: seminomatous germ; metastatic potential; cell tumours; germ cell ... See more keywords
Epirubicin suppresses proliferative and metastatic potential by downregulating transforming growth factor‐β‐induced expression in urothelial carcinoma
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DOI: 10.1111/cas.13403
Abstract: Transforming growth factor‐β‐induced (TGFΒI) is considered to be a vital gene in several carcinomas. In this study we determined the effect of TGFBI on the proliferative and metastatic potential of human urothelial carcinoma (UC) cells… read more here.
Keywords: transforming growth; growth factor; proliferative metastatic; expression ... See more keywords
The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-1369
Abstract: Metastasis is responsible for the majority of deaths of cancer patients. However, mechanisms governing metastasis in colorectal cancer (CRC) remain largely unknown. Here we investigated how CRC cells acquire metastatic potential using a novel mouse… read more here.
Keywords: metastasis; cancer; crc; camp pka ... See more keywords
Abstract A26: The metastatic potential of breast cancer cells was suppressed by NLRP3 inflammasome inhibition in macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Immunotherapy"
DOI: 10.1158/1557-3125.advbc17-a26
Abstract: Tumor microenvironment favors tumor cells to promote tumor growth, migration, invasion, and angiogenesis. IL-1beta, one of the inflammatory cytokines associated with tumor microenvironment, plays an important role in the development and progress of tumor. The… read more here.
Keywords: breast cancer; cancer cells; cancer; metastatic potential ... See more keywords