Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression
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DOI: 10.1038/s41388-019-0852-0
Abstract: Metastatic breast cancer is an extremely complex disease with limited treatment options due to the lack of information about the major characteristics of metastatic disease. There is an urgent need, therefore, to understand the changes… read more here.
Keywords: signaling pathways; lung metastases; metastatic progression; wnt stat3 ... See more keywords
Cancer cells exploit an orphan RNA to drive metastatic progression
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DOI: 10.1038/s41591-018-0230-4
Abstract: Here we performed a systematic search to identify breast-cancer-specific small noncoding RNAs, which we have collectively termed orphan noncoding RNAs (oncRNAs). We subsequently discovered that one of these oncRNAs, which originates from the 3′ end… read more here.
Keywords: cells exploit; breast cancer; metastatic progression; cancer cells ... See more keywords
Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer
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DOI: 10.1093/annonc/mdx074
Abstract: Background Patients often ask oncologists how long a cancer has been present before causing symptoms or spreading to other organs. The evolutionary trajectory of cancers can be defined using phylogenetic approaches but lack of chronological… read more here.
Keywords: carbon; colorectal cancer; metastatic progression; cancer ... See more keywords
EP648 Subungual metastasis of an endometrial carcinoma
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DOI: 10.1136/ijgc-2019-esgo.704
Abstract: Introduction/Background Metastasis to the nail bed are rare in solid tumor especially endometrial carcinoma. The majority of reported cases are associated with lung, kidney and breast cancers. With only scarce reports on this presentation, subungual… read more here.
Keywords: metastasis; metastatic progression; endometrial carcinoma; subungual metastasis ... See more keywords
Abstract 4177: An IL13Rα2 peptide inhibits colorectal cancer metastatic progression
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DOI: 10.1158/1538-7445.am2018-4177
Abstract: Interleukin 13 receptor α2 (IL13Rα2) is an excellent tumoral marker for metastatic colorectal cancer and glioblastoma. Our goal was to block IL-13 binding to IL13Rα2 by using IL13Rα2 synthetic peptides in order to delay or… read more here.
Keywords: cancer; il13r peptide; metastatic progression; colorectal cancer ... See more keywords
Metastatic Progression of Osteosarcomas: A Review of Current Knowledge of Environmental versus Oncogenic Drivers
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DOI: 10.3390/cancers14020360
Abstract: Simple Summary Osteosarcomas are heterogeneous bone tumors with complex genetic and chromosomic alterations. The numerous patients with metastatic osteosarcoma have a very poor prognosis, and only those who can have full surgical resection of the… read more here.
Keywords: progression osteosarcomas; primary tumor; metastatic progression; knowledge ... See more keywords