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Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.4319
Abstract: Importance There is controversy about the benefit of prostate-specific antigen (PSA) screening. Prostate-specific antigen screening rates have decreased since 2008 in the US, and the incidence of metastatic prostate cancer has increased. However, there is…
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Keywords:
prostate cancer;
prostate;
metastatic prostate;
screening rates ... See more keywords
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Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5151
Abstract: The COVID‐19 pandemic disrupted prostate‐specific antigen (PSA) screening and prostate biopsy procedures. We sought to determine whether delayed screening and diagnostic workup of prostate cancer (PCa) was associated with increased subsequent rates of incident PCa…
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Keywords:
late pandemic;
prostate cancer;
prostate;
metastatic prostate ... See more keywords
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Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12312
Abstract: Abstract Bone metastases are still incurable and result in the development of clinical complications and decreased survival for prostate cancer patients. Recently, a number of studies have shown that extracellular vesicles (EVs) play important roles…
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Keywords:
prostate cancer;
extracellular vesicles;
prostate;
metastatic prostate ... See more keywords
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Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3681-9
Abstract: Background[177Lu]Lu-PSMA-617 is a well-tolerated therapy for the treatment of metastatic prostate cancer. However, because of the mainly renal excretion of the tracer, the kidneys are one of the most limiting organs. The purpose of this…
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Keywords:
psma 617;
177lu psma;
metastatic prostate;
prostate cancer ... See more keywords
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Published in 2020 at "World Journal of Urology"
DOI: 10.1007/s00345-020-03296-8
Abstract: Purpose The landscape of the management of metastatic prostate cancer is changing rapidly and there is growing interest in the local treatment of the primary in these patients. The effect of local treatment on the…
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Keywords:
prostate;
metastatic prostate;
local treatment;
prostate cancer ... See more keywords
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Published in 2017 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-017-3706-8
Abstract: PurposeFatigue is a prevalent and debilitating side effect of docetaxel chemotherapy in metastatic prostate cancer. A better understanding of the kinetics and nature of docetaxel-related fatigue may provide a framework for intervention.MethodsThis secondary analysis was…
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Keywords:
docetaxel related;
metastatic prostate;
fatigue;
related fatigue ... See more keywords
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Published in 2017 at "PharmacoEconomics"
DOI: 10.1007/s40273-017-0555-8
Abstract: BackgroundProstate cancer (PC) is the most common cancer in Western countries. More than one third of PC patients develop metastatic disease, and the 5-year expected survival in distant disease is about 35%. During the last…
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Keywords:
metastatic prostate;
treatment;
prostate cancer;
cancer ... See more keywords
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Published in 2019 at "Asian Journal of Urology"
DOI: 10.1016/j.ajur.2019.02.002
Abstract: The management of metastatic prostate cancer (mPCa) has changed over the past ten years. Several new drugs have been approved with significant overall survival benefits in metastatic castration resistant prostate cancer (PCa) including chemotherapy (docetaxel,…
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Keywords:
prostate;
metastatic prostate;
treatment;
prostate cancer ... See more keywords
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Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.06.039
Abstract: While mutations affecting protein-coding regions have been examined across many cancers, structural variants at the genome-wide level are still poorly defined. Through integrative deep whole-genome and -transcriptome analysis of 101 castration-resistant prostate cancer metastases (109X…
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Keywords:
prostate;
metastatic prostate;
genomic hallmarks;
prostate cancer ... See more keywords
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Published in 2019 at "Clinical genitourinary cancer"
DOI: 10.1016/j.clgc.2019.03.021
Abstract: INTRODUCTION Testosterone suppression in serum during androgen deprivation therapy (ADT) can affect the oncologic outcome of ADT. Although genetic variants in sex hormone-binding globulin (SHBG) were reported to be correlated with serum testosterone level, the…
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Keywords:
prostate;
testosterone;
cancer;
metastatic prostate ... See more keywords
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Published in 2020 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2020.102057
Abstract: Despite advances in metastatic prostate cancer therapy, expected survival for patients in the castration-resistant phase of disease is poor. Immune-checkpoints inhibitors significantly prolonged life expectancy in some solid tumors and have been evaluated also in…
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Keywords:
cancer;
metastatic prostate;
cancer therapy;
prostate cancer ... See more keywords