Abstract 2471: Novel Tetrazolo-pyridazine based MACC1 inhibitors are promising for anti-metastatic therapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2471
Abstract: Cancer metastasis is the most lethal attribute of cancer, frequently caused by insufficient therapies and limited therapy options. Novel compounds able to interfere with metastasis formation are therefore of tremendous interest. Colorectal Cancer (CRC) is… read more here.
Keywords: metastasis; crc; anti metastatic; metastatic therapy ... See more keywords
Extracellular Matrix Elasticity Promotes Metastatic Therapy Resistance.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2022-033
Abstract: Adaptation to oxidative stress in a soft microenvironment confers metastatic therapeutic resistance. read more here.
Keywords: matrix elasticity; elasticity promotes; resistance; promotes metastatic ... See more keywords