Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling.
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DOI: 10.1021/acsmedchemlett.8b00440
Abstract: Dissymmetric cross metathesis of alkenes as a convergent and general synthetic strategy allowed for the preparation of a new small series of human histone deacetylases (HDAC) inhibitors. Alkenes bearing Boc-protected hydroxamic acid and benzamide and… read more here.
Keywords: extending cross; metathesis identify; hdac inhibitors; cross metathesis ... See more keywords