Metered‐dose inhalers vs nebulization for the delivery of albuterol in pediatric asthma exacerbations: A cost‐effectiveness analysis in a middle‐income country
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24650
Abstract: Although the benefits of albuterol delivered via metered‐dose inhalers with a spacer (MDI+S) have been increasingly recognized, the evidence regarding the cost‐effectiveness of MDI+S compared to nebulization (NEB) is not sufficient, especially in less‐affluent countries,… read more here.
Keywords: dose inhalers; pediatric asthma; cost; metered dose ... See more keywords
Increasing the fine particle fraction of pressurised metered dose inhaler solutions with novel actuator shapes.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120341
Abstract: In this paper we demonstrate that the use of multiple orifices can improve the fine particle fraction (FPF) of pressurised metered-dose inhaler solution formulations by up to 75% when compared to a single orifice with… read more here.
Keywords: particle fraction; pressurised metered; fine particle; particle ... See more keywords
Development of nanodispersion-based sildenafil metered-dose inhalers stabilized by poloxamer 188: a potential candidate for the treatment of pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2019.1650766
Abstract: Abstract Objectives: This study aims to formulate nanodispersion-based sildenafil metered-dose inhalers (MDIs) by using poloxamer 188 (P188) as a stabilizer; to evaluate their stability, aerosol characteristics, cytotoxicity, and inflammatory effects; and to investigate the effects… read more here.
Keywords: nanodispersion based; sildenafil; based sildenafil; metered dose ... See more keywords
Asthma 101: Teaching children to use metered dose inhalers.
Sign Up to like & getrecommendations! Published in 2019 at "Nursing"
DOI: 10.1097/01.nurse.0000552703.80996.43
Abstract: Providers across the spectrum of healthcare must be aware of their patients' inhaler use. This article addresses common errors and the proper use of pressurized metered-dose inhalers in pediatric patients. read more here.
Keywords: dose inhalers; metered dose; teaching children; children use ... See more keywords
Advanced counselling using training device and smartphone application on inhalation technique from metered‐dose inhaler with spacer equipped with different interfaces in asthmatic children
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Practice"
DOI: 10.1111/ijcp.14413
Abstract: Spacers are equipped with either facemask or mouthpiece as an interface through which patient inhale their dose. The present study aimed to evaluate the effect of advanced counselling using training devices and smartphone applications on… read more here.
Keywords: counselling using; advanced counselling; spacer equipped; dose inhaler ... See more keywords
Barriers to green inhaler prescribing: ethical issues in environmentally sustainable clinical practice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Ethics"
DOI: 10.1136/jme-2022-108388
Abstract: The National Health Service (NHS) was the first healthcare system globally to declare ambitions to become net carbon zero. To achieve this, a shift away from metered-dose inhalers which contain powerful greenhouse gases is necessary.… read more here.
Keywords: inhaler; environmentally sustainable; practice; barriers green ... See more keywords
Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/1753466620916990
Abstract: Background: Functional respiratory imaging (FRI) is a quantitative postprocessing imaging technique used to assess changes in the respiratory system. Using FRI, we characterized the effects of the long-acting muscarinic antagonist (LAMA), glycopyrrolate metered dose inhaler… read more here.
Keywords: metered dose; respiratory imaging; mdi; functional respiratory ... See more keywords
Competence in metered dose inhaler technique among community pharmacy professionals in Gondar town, Northwest Ethiopia: Knowledge and skill gap analysis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0188360
Abstract: Background When compared to systemic administration, if used correctly inhalers deliver a smaller enough percent of the drug right to the site of action in the lungs, with a faster onset of effect and with… read more here.
Keywords: community; dose inhaler; metered dose; community pharmacy ... See more keywords
Parental perceptions about the use of Metered dose inhaler vs Nebulizer in children with acute asthma exacerbation
Sign Up to like & getrecommendations! Published in 2018 at "Pediatrics"
DOI: 10.1542/peds.142.1_meetingabstract.582
Abstract: Purpose:Metered-dose inhalers (MDI) with a spacer are as good as, or better than, nebulizers for the management of children with asthma exacerbation. Numerous randomized controlled trials that compared outcomes such as hospital admission rates, asthma… read more here.
Keywords: parental perceptions; use metered; asthma exacerbation; metered dose ... See more keywords
Molecular Dynamic Simulation Approach to Predict the Compatibility of Formulation Components of Salbutamol Sulfate Metered Dose Inhaler Free off Ethanol
Sign Up to like & getrecommendations! Published in 2023 at "Research Journal of Pharmacy and Technology"
DOI: 10.52711/0974-360x.2023.00228
Abstract: More than 50 years since the first introduction of metered dose inhaler (MDI) by Riker laboratories 1956. The major development in MDI manufacturing was the transformation from chloroflouro carbon (CFC) to hydroflouro alkane (HFA) which… read more here.
Keywords: formulation; metered dose; simulation; mdi ... See more keywords