Sandwich‐Structured Nanofiber Dressings Containing MgB2 and Metformin Hydrochloride With ROS Scavenging and Antibacterial Properties for Wound Healing in Diabetic Infections
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402452
Abstract: The treatment of chronic diabetic wounds is a major challenge due to oxidative stress, persistent hyperglycemia, and susceptibility to bacterial infection. In this study, multifunctional sandwich‐structured nanofiber dressings (SNDs) are prepared via electrospinning. The SNDs… read more here.
Keywords: structured nanofiber; metformin hydrochloride; sandwich structured; mgb2 ... See more keywords
Volumetric, Acoustic and Transport Properties of Metformin Hydrochloride Drug in Aqueous d-Glucose Solutions at T = (298.15–318.15) K
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Solution Chemistry"
DOI: 10.1007/s10953-017-0584-0
Abstract: Apparent molar volumes, apparent molar adiabatic compressibilities and viscosity B-coefficients for metformin hydrochloride in aqueous d-glucose solutions were determined from solution densities, sound velocities and viscosities measured at T = (298.15–318.15) K and at pressure p = 101 kPa as… read more here.
Keywords: molar adiabatic; metformin hydrochloride; apparent molar; 298 318 ... See more keywords
E.P.A.S.S: Electroanalytical Pillbox Assessment Sensor System, A Case Study Using Metformin Hydrochloride.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00611
Abstract: Adulteration of medications is an emerging and significant threat to human health and well-being, even though adulterants are still often not considered seriously in clinical or forensic toxicology. Screening of drug adulterations is a major… read more here.
Keywords: electroanalytical pillbox; assessment sensor; adulteration; pillbox assessment ... See more keywords
Transdermal Cubic Phases of Metformin Hydrochloride: In Silico and in Vitro Studies of Delivery Mechanisms.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00209
Abstract: Transdermal delivery is one of important controlled drug release strategies for drug development. Cubic phases are the assemblies of amphiphilic molecules in water with the hydrophilic-hydrophobic interpenetrating network for transdermal delivery of both hydrophilic and… read more here.
Keywords: transdermal delivery; cubic phases; delivery; drug ... See more keywords
Determination and Correlation of Solubility of Metformin Hydrochloride in Aqueous Binary Solvents from 283.15 to 323.15 K
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06468
Abstract: Metformin hydrochloride (MET·HCl) is one of the most widely used oral hypoglycemic drugs in the world. In addition to hypoglycemic effects, MET·HCl also has anti-inflammatory, anti-tumor, anti-aging, and other effects, showing good efficacy and safety… read more here.
Keywords: met hcl; solubility; water; correlation ... See more keywords
Enhancing diabetes therapy with pH-sensitive co-delivery of metformin hydrochloride and glipizide using MCM-48-based dual drug delivery system
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d5ra00204d
Abstract: Monotherapy in diabetes management is losing interest due to its ineffectiveness in achieving optimal glycaemic control in a significant proportion of diabetic patients. Therefore, combined therapy is increasingly preferred by clinicians, which offers enhanced effectiveness… read more here.
Keywords: dual drug; metformin hydrochloride; delivery; drug ... See more keywords
Preparation and characterisation of self-emulsifying drug delivery system (SEDDS) for enhancing oral bioavailability of metformin hydrochloride using hydrophobic ion pairing complexation
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2023.2170488
Abstract: Abstract Aim The aim of this study was preparation of a self-emulsifying drug delivery system (SEEDS) containing metformin hydrochloride. Methods Hydrophobic ion paired complexes were prepared by electrostatic interaction between metformin and sodium lauryl sulphate… read more here.
Keywords: self emulsifying; delivery system; emulsifying drug; drug delivery ... See more keywords
Bioequivalence and safety evaluation of two preparations of metformin hydrochloride sustained-release tablets (Boke® and Glucophage®-XR) in healthy Chinese volunteers: a randomized phase I clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2125574
Abstract: Abstract Background As per the National Medical Products Administration (NMPA) requirements, the quality and efficacy of generic drugs must be consistent with those of the innovator drug. We aimed to evaluate the bioequivalence and safety… read more here.
Keywords: glucophage; bioequivalence; bioequivalence safety; healthy chinese ... See more keywords
Metformin hydrochloride and wound healing: from nanoformulation to pharmacological evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2018.1556291
Abstract: Abstract Niosomes as drug delivery systems have the ability to decrease drugs' side effects and increase their therapeutic effectiveness. Metformin HCl is an oral antihyperglycemic agent belonging to biguanides. It is the most commonly chosen… read more here.
Keywords: wound healing; metformin hcl; hydrochloride wound; metformin hydrochloride ... See more keywords
DoE-based Analytical Failure Modes Critical Effect Analysis (AFMCEA) to Multipurpose-RP-HPLC Method for Estimation of Multiple FDC Products of Metformin Hydrochloride Using Analytical Quality by Design Approach.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac025
Abstract: BACKGROUND Metformin hydrochloride is the first choice antihyperglycemic agent and its several fixed-dose combinations (FDCs) with pioglitazone hydrochloride, sitagliptin phosphate and gliclazide are used for the management of type II diabetes. Numerous RP-HPLC and HPTLC… read more here.
Keywords: metformin hydrochloride; method; estimation; approach ... See more keywords
Validation and Application of Screen-Printed Microchip for Potentiometric Determination of Metformin Hydrochloride in Tablet Dosage Form
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Analytical Chemistry"
DOI: 10.1155/2024/8664723
Abstract: Metformin is an oral biguanides hypoglycaemic agent, which used to lower the blood glucose levels in people with type 2 diabetes mellitus. Many analytical techniques have been used to quantify the drug in different pharmaceutical… read more here.
Keywords: method; dosage; metformin hydrochloride; dosage form ... See more keywords