Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension
Sign Up to like & getrecommendations! Published in 2024 at "Acta Physiologica"
DOI: 10.1111/apha.14226
Abstract: Metformin has been attributed to cardiovascular protection even in the absence of diabetes. Recent observations suggest that metformin influences the gut microbiome. We aimed to investigate the influence of metformin on the gut microbiota and… read more here.
Keywords: modulates microbiota; metformin modulates; improves blood; microbiota improves ... See more keywords
Metformin Modulates Cell Oxidative Stress to Mitigate Corticosteroid-Induced Suppression of Osteogenesis in a 3D Model
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DOI: 10.2147/jir.s498888
Abstract: Background Corticosteroids provide well-established therapeutic benefits; however, they are also accompanied by adverse effects on bone. Metformin is a widely used medication for managing type 2 diabetes mellitus. Recent studies have highlighted additional therapeutic benefits… read more here.
Keywords: metformin modulates; stress; oxidative stress; osteogenesis ... See more keywords
Metformin modulates oxidative stress via activation of AMPK/NF-κB signaling in Trisomy 21 fibroblasts: an in vitro study
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2025.1577044
Abstract: Introduction Oxidative stress and impaired antioxidant defenses are key contributors to cellular dysfunction in Trisomy 21 (T21), highlighting the need for targeted therapeutic strategies. This study explores the modulatory effects of metformin on oxidative stress… read more here.
Keywords: metformin modulates; stress; oxidative stress; study ... See more keywords