Metformin Plus Caloric Restriction Show Anti-epileptic Effects Mediated by mTOR Pathway Inhibition
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-018-0611-8
Abstract: Caloric restriction (CR) has anti-epileptic effects in different animal models, at least partially due to inhibition of the mechanistic or mammalian target of rapamycin (mTOR) signaling pathway. Adenosine monophosphate-activated protein kinase (AMPK) inhibits mTOR cascade… read more here.
Keywords: anti epileptic; caloric restriction; metformin plus; inhibition ... See more keywords
Effectiveness of triple therapy with dapagliflozin add-on to dual therapy over 52 weeks in patients with uncontrolled type 2 diabetes mellitus in a centre of high complexity, Cali-Colombia.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of endocrinology and metabolism"
DOI: 10.20945/2359-3997000000319
Abstract: Objective To evaluate the effectiveness of adding dapagliflozin as an intensification strategy for the treatment of patients with uncontrolled type 2 diabetes mellitus (T2DM). Methods A historical cohort study was conducted in 123 adult patients… read more here.
Keywords: therapy; metformin plus; patients uncontrolled; dapagliflozin add ... See more keywords
2320-PUB: Effects of Sequential Therapy Using Metformin plus Pioglitazone following Short-Term Intensive Insulin Therapy in Patients with Newly Diagnosed T2DM
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DOI: 10.2337/db19-2320-pub
Abstract: Aims: Short-term intensive insulin therapy (SIIT) reverses β cell dysfunction in early T2DM, but this effect vanes overtime. This study aimed to investigate the effects of metformin plus pioglitazone sequential therapy on maintenance of the… read more here.
Keywords: therapy; sequential therapy; insulin; metformin plus ... See more keywords
Sodium Glucose Cotransporter-2 Inhibitors as an Add-on Therapy to Metformin Plus Dipeptidyl Peptidase-4 Inhibitor in Patients with Type 2 Diabetes
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DOI: 10.3349/ymj.2022.63.6.539
Abstract: Purpose To date, no study has compared the effects of adding sodium glucose cotransporter-2 (SGLT-2) inhibitors to the combination of metformin plus dipeptidyl peptidase-4 (DPP-4) inhibitors to the effects of adding other conventional anti-diabetic drugs… read more here.
Keywords: add therapy; inhibitor; therapy; metformin plus ... See more keywords