Metformin selectively targets redox control of complex I energy transduction
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DOI: 10.1016/j.redox.2017.08.018
Abstract: Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only the biguanide metformin has enjoyed sustained clinical use. Here, we have isolated unique mitochondrial redox control properties of metformin that are… read more here.
Keywords: metformin selectively; redox control; energy transduction;