Development of Osteoarthritis in Adults With Type 2 Diabetes Treated With Metformin vs a Sulfonylurea
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.3646
Abstract: Key Points Question Is metformin use associated with incidence of osteoarthritis (OA)? Findings In this cohort study including 41 874 time-conditional propensity score–matched patients using metformin or a sulfonylurea, those treated with metformin had a lower… read more here.
Keywords: osteoarthritis adults; development osteoarthritis; metformin sulfonylurea; treated metformin ... See more keywords
Metformin vs sulfonylurea use and risk of dementia in US veterans aged ≥65 years with diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Neurology"
DOI: 10.1212/wnl.0000000000004586
Abstract: Objective: To determine whether metformin is associated with a lower incidence of dementia than sulfonylureas. Methods: This was a retrospective cohort study of US veterans ≥65 years of age with type 2 diabetes who were… read more here.
Keywords: risk dementia; dementia; age; years age ... See more keywords
rs622342 in SLC22A1, CYP2C9*2 and CYP2C9*3 and Glycemic Response in Individuals with Type 2 Diabetes Mellitus Receiving Metformin/Sulfonylurea Combination Therapy: 6-Month Follow-Up Study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm10020053
Abstract: Background and Objective: Since the treatment outcome with oral anti-diabetics differs between individuals, the objective of this study is to evaluate the significance of rs622342 in SLC22A1, CYP2C9*2 (rs1799853) and CYP2C9*3 (rs1057910) with regard to… read more here.
Keywords: metformin sulfonylurea; slc22a1 cyp2c9; cyp2c9; rs622342 slc22a1 ... See more keywords