Metformin upregulates mitophagy in patients with T2DM: A randomized placebo‐controlled study
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DOI: 10.1111/jcmm.14834
Abstract: Impaired mitochondrial autophagy (mitophagy) and NLRP3 inflammasome activation have been incriminated in the pathogenesis of T2DM. Metformin besides being an insulin sensitizer also induces autophagy; however, its effect on mitophagy and NLRP3 activation in patients… read more here.
Keywords: placebo; upregulates mitophagy; metformin upregulates; patients t2dm ... See more keywords