Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2018.0292
Abstract: Importance Approximately 1 million patients in the United States with type 2 diabetes mellitus and mild-to-moderate kidney disease do not receive guideline-directed therapy with metformin. This may reflect uncertainty regarding the risk of acidosis in… read more here.
Keywords: acidosis; use; egfr min; metformin ... See more keywords
Metformin use and hospital attendance‐related resources utilization among diabetic patients with prostate cancer on androgen deprivation therapy: A population‐based cohort study
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5651
Abstract: Androgen deprivation therapy (ADT), used increasingly in the treatment of prostate cancer (PCa), negatively influences glycemic control in diabetes and is associated with an increased risk of diabetes complications where hospitalization commonly ensues. Metformin could… read more here.
Keywords: prostate cancer; deprivation therapy; androgen deprivation; resources utilization ... See more keywords
60 years of metformin use: a glance at the past and a look to the future
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4343-y
Abstract: This year marks the 60th anniversary of the first clinical use of metformin for diabetes. From small beginnings (and despite a somewhat chequered history), metformin is currently recommended as the first-line oral glucose-lowering agent in… read more here.
Keywords: use; metformin; metformin use; drug ... See more keywords
Metformin use and risk of fracture: a systematic review and meta-analysis of observational studies
Sign Up to like & getrecommendations! Published in 2019 at "Osteoporosis International"
DOI: 10.1007/s00198-019-04948-1
Abstract: IntroductionNo study is available summarizing earlier publications on the association between metformin use and risk of fracture. This systematic review and meta-analysis were conducted to summarize earlier findings on the association between metformin use and… read more here.
Keywords: risk; risk fracture; systematic review; metformin use ... See more keywords
The impact of metformin use on survival in kidney cancer patients with diabetes: a meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1548-4
Abstract: PurposeThe effects of metformin on the prognosis of kidney cancer patients with diabetes are in controversial. The present study is conducted to classify the association of metformin use with the survival of patients with kidney… read more here.
Keywords: kidney; metformin use; cancer; cancer patients ... See more keywords
Review of Metformin Use for Type 2 Diabetes Prevention.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of preventive medicine"
DOI: 10.1016/j.amepre.2018.04.038
Abstract: CONTEXT Prediabetes is prevalent and significantly increases lifetime risk of progression to type 2 diabetes. This review summarizes the evidence surrounding metformin use for type 2 diabetes prevention. EVIDENCE ACQUISITION Articles published between 1998 and… read more here.
Keywords: diabetes prevention; prevention; metformin use; evidence ... See more keywords
Metformin use and lung cancer survival: a population-based study in Norway.
Sign Up to like & getrecommendations! Published in 2020 at "British journal of cancer"
DOI: 10.1038/s41416-020-01186-9
Abstract: BACKGROUND We assessed associations between metformin use and survival in a nationwide Norwegian cohort of lung cancer (LC) patients. METHODS The study linked 22,324 LC patients from the Cancer Registry of Norway diagnosed 2005-2014 with… read more here.
Keywords: survival; metformin use; use; lung cancer ... See more keywords
Metformin Use and Severe Dengue in Diabetic Adults
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21612-6
Abstract: Diabetes mellitus is a risk factor for severe dengue in adults, but few studies have examined the association between metformin use and disease severity in dengue. In addition to its effect on glucose control, metformin… read more here.
Keywords: dengue; severity; metformin use; severe dengue ... See more keywords
Survival Benefits From Metformin Use in Pancreatic Cancer: A Systemic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Pancreas"
DOI: 10.1097/mpa.0000000000001000
Abstract: 4 cases of pancreatitis (1.98%). In these cases, the admission length of stay was 4, 7, 14, and 15 days. This subgroup of patients with pancreatitis had a significantly longer inpatient stay than that noted… read more here.
Keywords: survival benefits; metformin use; pancreatic cancer; cancer systemic ... See more keywords
Impact of Metformin Use on Lactate Kinetics in Patients with Severe Sepsis and Septic Shock
Sign Up to like & getrecommendations! Published in 2017 at "SHOCK"
DOI: 10.1097/shk.0000000000000782
Abstract: Background: We aimed to evaluate the impact of metformin use on lactate kinetics in patients with severe sepsis and septic shock. Methods: We analyzed data from a registry that included patients who presented to the… read more here.
Keywords: sepsis septic; severe sepsis; metformin; metformin use ... See more keywords
Association between oral metformin use and the risk of age-related macular degeneration: A systematic review with meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Acta ophthalmologica"
DOI: 10.1111/aos.15655
Abstract: Rodent studies demonstrate that oral metformin use may reduce chronic low-grade inflammation, downregulate apoptosis and extend life span. Emerging epidemiological evidence suggests that oral metformin use may protect against development of age-related macular degeneration (AMD)… read more here.
Keywords: metformin; risk; oral metformin; association ... See more keywords