Compulsive methamphetamine taking induces autophagic and apoptotic markers in the rat dorsal striatum
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Toxicology"
DOI: 10.1007/s00204-020-02844-w
Abstract: Methamphetamine (METH) use disorder (MUD) is often accompanied by psychotic symptoms, cognitive deficits, and pathological changes in the brains of users. Animals that experimenters injected with drugs also show neurodegenerative changes in their brains. Recently,… read more here.
Keywords: rat dorsal; methamphetamine; dorsal striatum; changes brains ... See more keywords
Repeated restraint stress reduces the acquisition and relapse of methamphetamine-conditioned place preference but not behavioral sensitization
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2018.01.018
Abstract: The studies for the effects of stress on drug addiction were mostly obtained using sequential exposure to stress and drugs. However, few studies have been conducted on the effects of simultaneous exposure to stress and… read more here.
Keywords: exposure; stress; restraint stress; meth ... See more keywords
Fas and GIT1 signalling in the prefrontal cortex mediate behavioural sensitization to methamphetamine in mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.07.001
Abstract: PURPOSE Repeated methamphetamine (METH) administration in mice readily produces behavioural sensitization, but the underlying mechanisms remain elusive. The present research aimed to identify new targets affecting METH-induced behavioural sensitization. METHODS We first established a mouse… read more here.
Keywords: behavioural sensitization; fas git1; sensitization; meth ... See more keywords
Synthesis and biological evaluation of a lipopeptide-based methamphetamine vaccine
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.10.038
Abstract: Abstract We describe an application of carrier protein-free strategy in constructing a fully synthetic methamphetamine (METH) vaccine that contains three components: Toll-like receptor 2 ligand, Th2 epitope, and METH hapten. The immunological evaluation in mice… read more here.
Keywords: biological evaluation; meth; vaccine; lipopeptide based ... See more keywords
Environmental behavior of methamphetamine and ketamine in aquatic ecosystem: Degradation, bioaccumulation, distribution, and associated shift in toxicity and bacterial community.
Sign Up to like & getrecommendations! Published in 2020 at "Water research"
DOI: 10.1016/j.watres.2020.115585
Abstract: Ketamine (KET) and methamphetamine (METH) have been recognized as emerging contaminants in aquatic ecosystems. This paper aimed to investigate the environmental behaviour, including the degradation, distribution, and bioaccumulation, of METH, KET, and their main metabolites… read more here.
Keywords: ket; water; toxicity; meth ket ... See more keywords
Antibody-Conjugated Electrospun Nanofibers for Electrochemical Detection of Methamphetamine
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.3c02266
Abstract: Multifunctional electrospun nanofibers (ENs) with improved properties have increased attention nowadays. Their insoluble forms in water with decreased hydrophobicity are desired for the immobilization of biological molecules. Also, the addition of functional groups on the… read more here.
Keywords: anti meth; meth; detection; pvdf pei ... See more keywords
The effect of methamphetamine abuse on dental caries and periodontal diseases in an Eastern China city
Sign Up to like & getrecommendations! Published in 2018 at "BMC Oral Health"
DOI: 10.1186/s12903-017-0463-5
Abstract: BackgroundDental diseases are among the most frequently reported health problems in drug abusers. However, few studies have been conducted on oral health of methamphetamine (meth) abusers in China. The aim of the present study was… read more here.
Keywords: periodontal diseases; eastern china; caries periodontal; dental caries ... See more keywords
miR-210 expression is associated with methionine-induced differentiation of trout satellite cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Experimental Biology"
DOI: 10.1242/jeb.154484
Abstract: ABSTRACT In fish, data on microRNAs (miRNAs) involved in myogenesis are scarce. In order to identify miRNAs involved in satellite cell differentiation, we used a methionine depletion/replenishment protocol to synchronize myogenic cell differentiation. Our results… read more here.
Keywords: methionine; expression; differentiation; mir 210 ... See more keywords
A Medical Marker for Diagnosis of Methamphetamine Addiction - DNA Methylation of SHATI/NAT8L Promoter Sites from Patient Blood.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200110111703
Abstract: BACKGROUND Methamphetamine (METH) is one of the most widely distributed psychostimulants in worldwide. Despite active Countermeasures taken by different countries, neither the overall usage of METH nor the frequency of repeat users has reduced over… read more here.
Keywords: dna methylation; shati nat8l; nat8l promoter; meth ... See more keywords
Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence.
Sign Up to like & getrecommendations! Published in 2021 at "Epigenomics"
DOI: 10.2217/epi-2020-0463
Abstract: Aim: We investigated DNA methylation of BDNFÂ in methamphetamine (METH) dependence in humans and an animal model. Materials & methods: BDNF methylation at exon IV was determined by pyrosequencing of blood DNA from METH-dependent and control… read more here.
Keywords: methylation; dependence; meth; dna methylation ... See more keywords
Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.940798
Abstract: The deleterious effects of methamphetamine (METH) exposure extend beyond abusers, and may potentially impact the vulnerability of their offspring in developing addictive behaviors. Epigenetic signatures have been implicated in addiction, yet the characteristics to identify… read more here.
Keywords: meth exposure; meth; behavioral sensitization; exposure ... See more keywords