Oxytocin Acts in Nucleus Accumbens to Attenuate Methamphetamine Seeking and Demand
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2016.11.011
Abstract: BACKGROUND Evidence indicates that oxytocin, an endogenous peptide well known for its role in social behaviors, childbirth, and lactation, is a promising addiction pharmacotherapy. We employed a within-session behavioral-economic (BE) procedure in rats to examine… read more here.
Keywords: methamphetamine; meth seeking; meth demand; nucleus accumbens ... See more keywords
Chemogenetic inhibition of corticostriatal circuits reduces cued reinstatement of methamphetamine seeking.
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DOI: 10.1111/adb.13097
Abstract: Methamphetamine (meth) causes enduring changes within the medial prefrontal cortex (mPFC) and the nucleus accumbens (NA). Projections from the mPFC to the NA have a distinct dorsal-ventral distribution, with the prelimbic (PL) mPFC projecting to… read more here.
Keywords: methamphetamine; reduces cued; meth seeking; cued reinstatement ... See more keywords
Adenosine receptor stimulation inhibits methamphetamine-associated cue seeking
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Psychopharmacology"
DOI: 10.1177/02698811221147157
Abstract: Background: Methamphetamine (METH) is a psychostimulant drug that remains a popular and threatening drug of abuse with high abuse liability. There is no established pharmacotherapy to treat METH dependence, but evidence suggests that stimulation of… read more here.
Keywords: cue; a1r a2ar; stimulation; adenosine receptor ... See more keywords