Current Concepts in Methadone Metabolism and Transport
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DOI: 10.1002/cpdd.326
Abstract: Methadone is a cornerstone therapy for opioid addiction and a public health strategy for HIV/AIDS and hepatitis C reduction. Methadone is also used for acute and chronic pain. As use for chronic pain has grown,… read more here.
Keywords: genetics; methadone; drug; methadone disposition ... See more keywords
Toward precision prescribing for methadone: Determinants of methadone deposition
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DOI: 10.1371/journal.pone.0231467
Abstract: Background Despite the World Health Organization listing methadone as an essential medication, effective dose selection is challenging, especially in racial and ethnic minority populations. Subtherapeutic doses can result in withdrawal symptoms while supratherapeutic doses can… read more here.
Keywords: cyp2b6; precision prescribing; methadone; toward precision ... See more keywords