Determination of methyl methanesulfonate and ethyl methanesulfonate in methanesulfonic acid by derivatization followed by high-performance liquid chromatography with ultraviolet detection.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700543
Abstract: Methanesulfonic acid is routinely used in pharmaceuticals but can contain potentially genotoxic impurities such as methyl methanesulfonate and ethyl methanesulfonate. The aim of this study was to develop a simple high-performance liquid chromatography with ultraviolet… read more here.
Keywords: methanesulfonate ethyl; methyl methanesulfonate; methanesulfonate; liquid chromatography ... See more keywords
Solid-liquid phase equilibrium in the water–Zn(II) methanesulfonate and water–Cu(II) methanesulfonate systems
Sign Up to like & getrecommendations! Published in 2018 at "Thermochimica Acta"
DOI: 10.1016/j.tca.2018.08.004
Abstract: Abstract Fragments of M(CH3SO3)2-H2O (M = Zn,Cu) phase diagrams from subsolidus temperatures up to 70 °C (343.15 K) were obtained. Melting parameters of anhydrous zinc methanesulfonate (Tm = 566.2 ± 0.3 K, ΔmH = 33.4 ± 0.6 kJ/mol) were clarified. New dodecahydrate zinc methanesulfonate and octahydrate copper… read more here.
Keywords: methanesulfonate; water methanesulfonate; solid liquid; liquid phase ... See more keywords
Determination of Methyl Methanesulfonate and Ethyl Methylsulfonate in New Drug for the Treatment of Fatty Liver Using Derivatization Followed by High-Performance Liquid Chromatography with Ultraviolet Detection
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27061950
Abstract: A new derivatization high-performance liquid chromatography method with ultraviolet detection was developed and validated for the quantitative analysis of methanesulfonate genotoxic impurities in an innovative drug for the treatment of non-alcoholic fatty liver disease. In… read more here.
Keywords: high performance; drug; derivatization; chromatography ... See more keywords