Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents.
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DOI: 10.1021/acsmedchemlett.1c00652
Abstract: The 6-trifluoro substituted 8-nitrobenzothiazinones (BTZs) represent a novel type of antitubercular agents, and their high antimycobacterial activity is related to the inhibition of decaprenylphosphoryl-β-d-ribose 2'-oxidase (DprE1), an enzyme essential for the biosynthesis of mycobacterial cell… read more here.
Keywords: development methanesulfonyl; methanesulfonyl nitrobenzothiazinone; nitrobenzothiazinone based; methanesulfonyl ... See more keywords