Pyrimidine Nucleotides Containing a (S)-Methanocarba Ring as P2Y6 Receptor Agonists.
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DOI: 10.1039/c7md00397h
Abstract: Both agonists and antagonists of the UDP-activated P2Y6 receptor (P2Y6R) have been proposed for therapeutic use, in conditions such as cancer, inflammation, neurodegeneration and diabetes. Uracil nucleotides containing a South-bicyclo[3.1.0]hexane ((S)-methanocarba) ring system in place… read more here.
Keywords: nucleotides containing; methanocarba ring; pyrimidine nucleotides; p2y6 receptor ... See more keywords