Synthesis of 5-aryl-3,3′-bis-indolyl and bis-7-aza-indolyl methanone derivatives from 5-bromo-7-azaindoles via sequential methylenation using microwave irradiation, CAN oxidation, and Suzuki coupling reactions
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DOI: 10.1039/d2ra05849a
Abstract: A catalyst-free and green chemical method has been developed for the methylenation of indole and N-methyl-7-aza indoles with aqueous formaldehyde afforded respective N,N′-dimethyl-3,3′-bis-7-azaindolylmethanes under microwave irradiation in excellent yield. Subsequent oxidation of the products thus… read more here.
Keywords: suzuki coupling; bis; methanone derivatives; methylenation ... See more keywords
Synthesis of one-pot pyrazolo[4′,3′:5,6]pyrano[2,3-c]phenazin-15-yl) methanone derivatives via a multi-component using Fe3O4@TiO2-SO3H as a recoverable magnetic catalyst under microwave irradiation
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DOI: 10.1080/17518253.2020.1794056
Abstract: ABSTRACT A new one-pot method for the synthesis four-component of pyrazolo[4′,3′:5,6]pyrano[2,3-c]phenazin-15-yl)methanone derivatives has been developed in the presence of nano Fe3O4@TiO2-SO3H catalysts (heterogeneous acid) under microwave conditions and in a solvent-free environment at 180 W. One… read more here.
Keywords: methanone derivatives; pyrazolo pyrano; one pot; pyrano phenazin ... See more keywords