Successful treatment of methazolamide‐induced toxic epidermal necrolysis in a Han Chinese patient with HLA‐B*59:01 and HLA‐Cw*01:02
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DOI: 10.1111/dth.13862
Abstract: Dear Editor, A 60-year-old man presented to our hospital's Emergency Department with multiple erythematous lesions, blisters on the trunk and limbs, and mucosal erosion. He had started taking methazolamide (100 mg/day) 3 weeks earlier for… read more here.
Keywords: hla alleles; methazolamide induced; hla; hla hla ... See more keywords
Genetic markers for methazolamide‐induced Stevens–Johnson syndrome and toxic epidermal necrolysis
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DOI: 10.1111/jdv.18158
Abstract: life-threatening, severe cutaneous adverse reactions characterized by varying extents of epidermal and mucosal The mortality rate associated with SJS/TEN depends on the severity of the disease, with typical mortality rates of between 1% and 5%… read more here.
Keywords: induced stevens; methazolamide induced; genetic markers; johnson syndrome ... See more keywords
Association of HLA-C*01:02 with methazolamide-induced toxic epidermal necrolysis
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DOI: 10.1136/bcr-2022-250048
Abstract: We identified a Yi Chinese female patient from an ethnic minority group with methazolamide-induced toxic epidermal necrolysis. Genotyping revealed that she and her immediate family members carried the HLA-C*01:02 haplotypes, known to be associated with… read more here.
Keywords: toxic epidermal; induced toxic; association hla; methazolamide induced ... See more keywords