Comparative Proteomic Profiling of Methicillin‐Susceptible and Resistant Staphylococcus aureus
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DOI: 10.1002/pmic.201900221
Abstract: Staphylococcus aureus is a highly successful human pathogen responsible for a wide range of infections. This study provides insights into the virulence, pathogenicity, and antimicrobial resistance determinants of methicillin‐susceptible and methicillin‐resistant S. aureus (MSSA; MRSA)… read more here.
Keywords: methicillin susceptible; staphylococcus aureus; proteomic profiling;
Association between early chronic methicillin‐susceptible Staphylococcus aureus colonization and lung function in children with cystic fibrosis
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DOI: 10.1002/ppul.26114
Abstract: Our aim was to determine whether early chronic methicillin‐susceptible Staphylococcus aureus (MSSA) colonization in children with cystic fibrosis (CF) is associated at 8 years of age with poorer lung function, poorer nutritional status, and increased… read more here.
Keywords: methicillin susceptible; chronic methicillin; staphylococcus aureus; early chronic ... See more keywords
The Safety and Economic Impact of Cefazolin versus Nafcillin for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections
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DOI: 10.1007/s40121-017-0148-z
Abstract: IntroductionAnti-staphylococcal penicillins are generally accepted as first-line therapy for methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, but their use may be limited by interstitial nephritis and acute kidney injury. Alternatives include first-generation cephalosporins including cefazolin.MethodsWe conducted a… read more here.
Keywords: methicillin susceptible; staphylococcus aureus; susceptible staphylococcus; cefazolin ... See more keywords
Nafcillin versus cefazolin for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of infection and public health"
DOI: 10.1016/j.jiph.2018.02.004
Abstract: BACKGROUND Anti-staphylococcal penicillins have long been the first-line treatment option for methicillin-susceptible Staphylococcus aureus (MSSA) infections. Recent retrospective data comparing nafcillin and cefazolin report similar clinical efficacy despite concerns about high inoculum MSSA infections. METHODS… read more here.
Keywords: methicillin susceptible; staphylococcus aureus; susceptible staphylococcus; treatment ... See more keywords
High frequency of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in children under 1 year old with skin and soft tissue infections.
Sign Up to like & getrecommendations! Published in 2018 at "Jornal de pediatria"
DOI: 10.1016/j.jped.2017.06.020
Abstract: OBJECTIVE Staphylococcus aureus is responsible for a large number of infections in pediatric population; however, information about the behavior of such infections in this population is limited. The aim of the study was to describe… read more here.
Keywords: methicillin; methicillin susceptible; staphylococcus aureus; aureus ... See more keywords
Multi-omics based characterization of antibiotic response in clinical isogenic isolates of methicillin-susceptible/-resistant Staphylococcus aureus
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DOI: 10.1039/d0ra05407k
Abstract: As demands for new antibiotics and strategies to control methicillin-resistant Staphylococcus aureus (MRSA) increase, there have been efforts to obtain more accurate and abundant information about the mechanism of the bacterial responses to antibiotics. However,… read more here.
Keywords: methicillin susceptible; staphylococcus aureus; multi omics; response ... See more keywords
Predominance of community-associated, methicillin-susceptible Staphylococcus aureus infections among hospitalized children and adolescents.
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DOI: 10.1099/jmm.0.001511
Abstract: Introduction. Staphylococcus aureus infections cause significant morbidity and mortality in children and adolescents.Gap Statement. There is limited data on the characteristics of S. aureus infections requiring hospitalization in childhood.Aim.To investigate the molecular epidemiology and antibiotic… read more here.
Keywords: community; methicillin susceptible; aureus infections; children adolescents ... See more keywords
Is the Success of Cefazolin plus Ertapenem in Methicillin-Susceptible Staphylococcus aureus Bacteremia Based on Release of Interleukin-1 Beta?
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DOI: 10.1128/aac.02166-21
Abstract: Cefazolin and ertapenem have been shown to be an effective salvage regimen for refractory methicillin-susceptible Staphylococcus aureus bacteremia. Our findings suggest cefazolin plus ertapenem in vitro stimulates interleukin-1β release from peripheral blood monocytes both with… read more here.
Keywords: methicillin susceptible; bacteremia; cefazolin plus; plus ertapenem ... See more keywords
Prevalence and Characterization of the Cefazolin Inoculum Effect in North American Methicillin-Susceptible Staphylococcus aureus Isolates
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DOI: 10.1128/jcm.02495-21
Abstract: Antistaphylococcal penicillins and cefazolin remain the primary treatments for infections with methicillin-susceptible Staphylococcus aureus (MSSA). The cefazolin inoculum effect (CzIE) causes the cefazolin MIC to be elevated in proportion to the number of bacteria in… read more here.
Keywords: methicillin susceptible; inoculum; microbiology; mssa ... See more keywords
Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections
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DOI: 10.1128/spectrum.01039-22
Abstract: Cephalexin and cefadroxil are oral antibiotics that are used to treat serious infections due to the bacteria MSSA. While cephalexin is used more commonly, cefadroxil is excreted from the body more slowly; this generally allows… read more here.
Keywords: methicillin susceptible; cefadroxil cephalexin; mssa; susceptible staphylococcus ... See more keywords
Does the Beta-Lactam Matter? Nafcillin versus Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections
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DOI: 10.1159/000499033
Abstract: Background: Antistaphylococcal penicillins have historically been regarded as the drugs of choice for methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections (BSI). However, recent outcomes data compared to cefazolin treatment are conflicting. Objective: This study compared treatment… read more here.
Keywords: methicillin susceptible; susceptible staphylococcus; treatment; treatment failure ... See more keywords