Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2397
Abstract: Experimental validation of enzyme function is crucial for genome interpretation, but it remains challenging because it cannot be scaled up to accommodate the constant accumulation of genome sequences. We tackled this issue for the MetA… read more here.
Keywords: biosynthesis; evolution non; methionine biosynthesis; isofunctional enzymes ... See more keywords
Methionine Limitation Impairs Pathogen Expansion and Biofilm Formation Capacity
Sign Up to like & getrecommendations! Published in 2019 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00177-19
Abstract: New antibiotics that attack novel targets are needed to circumvent widespread resistance to conventional drugs. Bacterial anabolic pathways, such as the enzymes for biosynthesis of the essential amino acid methionine, have been proposed as potential… read more here.
Keywords: methionine biosynthesis; methionine auxotrophs; inhibition; methionine ... See more keywords
Construction of exogenous methanol, formate, and betaine modules for methyl donor supply in methionine biosynthesis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1170491
Abstract: Methionine is an essential sulfur-containing amino acid that finds widespread applications in agriculture, medicine, and the food industry. However, the complex and multibranched biosynthetic pathway of methionine has posed significant challenges to its efficient fermentation… read more here.
Keywords: methanol; methionine biosynthesis; betaine; formate ... See more keywords
Propionate Attenuates Growth of Oral Streptococci through Enhancing Methionine Biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2205.05037
Abstract: Oral streptococci are considered as an opportunistic pathogen associated with initiation and progression of various oral diseases. However, since the currently-available treatments often accompany adverse effects, alternative strategy is demanded to control streptococci. In the… read more here.
Keywords: growth; growth oral; oral streptococci; methionine biosynthesis ... See more keywords