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Published in 2019 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2019.1694
Abstract: Importance Impairment of methylation status (ie, methionine to homocysteine ratio) may be a modifiable risk factor for structural brain changes and incident dementia. Objective To investigate the association of serum markers of methylation status and…
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Keywords:
risk dementia;
dementia;
homocysteine;
brain ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.7554/elife.76021
Abstract: The redox reagent dithiothreitol (DTT) causes stress in the endoplasmic reticulum (ER) by disrupting its oxidative protein folding environment, which results in the accumulation and misfolding of the newly synthesized proteins. DTT may potentially impact…
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Keywords:
dtt;
homocysteine cycle;
methionine homocysteine;
toxicity ... See more keywords