Vitamin B12, folate, and the methionine remethylation cycle—biochemistry, pathways, and regulation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12009
Abstract: Vitamin B12 (cobalamin, Cbl) is a nutrient essential to human health. Due to its complex structure and dual cofactor forms, Cbl undergoes a complicated series of absorptive and processing steps before serving as cofactor for… read more here.
Keywords: biochemistry; methionine; vitamin b12; cycle ... See more keywords
Methionine Synthase Deficiency: Variable Clinical Presentation And Benefit Of Early Diagnosis And Treatment.
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DOI: 10.1002/jimd.12448
Abstract: Methionine synthase deficiency (cblG complementation group) is a rare inborn error of metabolism affecting the homocysteine re-methylation pathway. It leads to a biochemical phenotype of hyperhomocysteinemia and hypomethioninemia. The clinical presentation of cblG is variable,… read more here.
Keywords: synthase deficiency; methionine; treatment; clinical presentation ... See more keywords
The complete electronic structure and mechanism of the methionine synthase process as determined by the MCSCF method
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2021.121811
Abstract: Abstract The methionine synthase process is regenerating the methionine from cysteine in the S-adenosylmethionine cycle running throughout several interactions and electron transfers between methylcobalamin cofactor and substrates. The methionine synthase process in connection with the… read more here.
Keywords: mechanism methionine; cofactor; process; synthase process ... See more keywords
Cobalamin-independent Methionine Synthase Distribution and Influence on Vitamin B12 Growth Requirements in Marine Diatoms.
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DOI: 10.1016/j.protis.2016.10.007
Abstract: The requirement for cobalamin (vitamin B12) in microalgae is primarily a function of the type of methionine synthase present within their gene repertoires. Our study validates this concept through analysis of the distribution of B12-independent… read more here.
Keywords: methionine synthase; vitamin b12; b12;
Suppression of a methionine synthase by calmodulin under environmental stress in the entomopathogenic fungus Beauveria bassiana
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DOI: 10.1111/1758-2229.12548
Abstract: Methionine synthase (MetE, EC 2.1.1.14) catalyses the final step in the methionine biosynthetic pathway. Methionine biosynthesis plays a major role in protein biogenesis and is the source of S-adenosyl methionine (SAM), the universal donor of… read more here.
Keywords: environmental stress; methionine; methionine synthase; entomopathogenic fungus ... See more keywords
Breed differences in the expression levels of gga-miR-222a in laying hens influenced H2S production by regulating methionine synthase genes in gut bacteria
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DOI: 10.1186/s40168-021-01098-7
Abstract: Background The microbiota in the cecum of laying hens is crucial for host digestion, metabolism, and odor gas production. The results of recent studies have suggested that host microRNAs (miRNAs) can regulate gene expression of… read more here.
Keywords: production; laying hens; methionine synthase; expression ... See more keywords
Impact of Methionine Synthase Reductase Polymorphisms in Chronic Myeloid Leukemia Patients
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DOI: 10.3390/genes13101729
Abstract: Highlights What are the main findings? Our objective was to determine the relationship between the methionine synthase reductase polymorphisms (MTRR and MTR) and the risk of developing chronic myeloid leukemia (CML) in Sudanese Patients. What… read more here.
Keywords: synthase reductase; chronic myeloid; myeloid leukemia; methionine synthase ... See more keywords
A Hydrogen-Sulfide-Repressed Methionine Synthase SlMS1 Acts as a Positive Regulator for Fruit Ripening in Tomato
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012239
Abstract: Ethylene is a key phytohormone that regulates the ripening of climacteric fruits, and methionine is an indirect precursor of ethylene. However, whether methionine synthase plays a role in fruit ripening in Solanum lycopersicum (tomato) is… read more here.
Keywords: positive regulator; fruit ripening; fruit; slms1 ... See more keywords