Highly sensitive liquid chromatographic method combined with online ion suppression to remove interfering anions and mass spectrometry for impurity profiling of paromomycin sulfate.
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DOI: 10.1002/jssc.202201012
Abstract: A previously developed high-performance liquid chromatography method combined with pulsed amperometric detection allowed to separate many impurities of paromomycin. However, due to the presence of ion pairing agents and sodium hydroxide in the mobile phase,… read more here.
Keywords: ion suppression; method combined; mass spectrometry; liquid ... See more keywords