Quadruple‐refocused spin‐locking: A robust method for high‐amplitude T1ρ imaging
Sign Up to like & getrecommendations! Published in 2025 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.30621
Abstract: Longitudinal relaxation time in the rotating frame (T1ρ) is a source of tissue‐specific contrasts, with applications in detecting myocardial fibrosis, liver fibrosis, and early‐stage osteoarthritis. However, T1ρ measurements are sensitive to static (B0) and radiofrequency… read more here.
Keywords: spin locking; refocused spin; robust method; method high ... See more keywords
A Method for High‐Throughput Screening of Monoclonal Antibody Internalization Using a DNA/Protein Molecular Staple
Sign Up to like & getrecommendations! Published in 2025 at "Small Methods"
DOI: 10.1002/smtd.202401399
Abstract: The use of monoclonal antibodies (mAbs) as therapeutics or for targeted delivery to specific cells is reliant on understanding mAb‐receptor interactions. Of particular importance is the relationship between mAb binding and internalization into cells. Internalization… read more here.
Keywords: receptor; internalization; method high; binding internalization ... See more keywords
A sensitive and validated LC-MS/MS method for high-throughput determination of pomalidomide in human plasma and pharmacokinetic studies
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.07.009
Abstract: ABSTRACT Pomalidomide is an immunomodulatory agent (IMiD) that has been approved by the Food and Drug Administration (FDA) for clinical treatment of patients with multiple myeloma. In this work, we developed a sensitive and validated… read more here.
Keywords: sensitive validated; method high; validated method; high throughput ... See more keywords
A Genetics-Free Method for High-Throughput Discovery of Cryptic Microbial Metabolites
Sign Up to like & getrecommendations! Published in 2019 at "Nature chemical biology"
DOI: 10.1038/s41589-018-0193-2
Abstract: Bacteria contain an immense untapped trove of novel secondary metabolites in the form of ‘silent’ biosynthetic gene clusters (BGCs). These can be identified bioinformatically but are not expressed under normal laboratory growth conditions. Methods to… read more here.
Keywords: genetics free; method high; genetics; free method ... See more keywords
A new method for high-precision palladium isotope analyses of iron meteorites and other metal samples
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Analytical Atomic Spectrometry"
DOI: 10.1039/c6ja00446f
Abstract: This paper presents a new method for high precision Pd isotope analyses in iron meteorites. First, Pd is separated from the sample matrix by a novel two-stage anion exchange procedure after which isotopic measurements are… read more here.
Keywords: iron meteorites; isotope analyses; method high; high precision ... See more keywords
Hard-thresholding regularization method for high-dimensional heterogeneous models
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Statistical Computation and Simulation"
DOI: 10.1080/00949655.2025.2461648
Abstract: Heterogeneity is often natural in many contemporary applications involving massive data, as exemplified by domains such as personalized education and tailored pricing strategy. In this article, we propose a new methodology for subgroup analysis via… read more here.
Keywords: thresholding regularization; method high; high dimensional; regularization method ... See more keywords
In situ compensation method for high-precision and high-sensitivity integral magnetometry
Sign Up to like & getrecommendations! Published in 2019 at "Measurement Science and Technology"
DOI: 10.1088/1361-6501/ab1b03
Abstract: An ongoing process of miniaturization of spintronics and magnetic-films-based devices, as well as a growing necessity for basic material research place stringent requirements for sensitive and accurate magnetometric measurements of minute magnetic constituencies deposited on… read more here.
Keywords: magnetometry; compensation; method high; method ... See more keywords
A Novel Convex Clustering Method for High-Dimensional Data Using Semiproximal ADMM
Sign Up to like & getrecommendations! Published in 2020 at "Mathematical Problems in Engineering"
DOI: 10.1155/2020/9216351
Abstract: Clustering is an important ingredient of unsupervised learning; classical clustering methods include K-means clustering and hierarchical clustering. These methods may suffer from instability because of their tendency prone to sink into the local optimal solutions… read more here.
Keywords: high dimensional; clustering method; method high; dimensional data ... See more keywords
Method of high-precision spatial distance measurement based on optical-carried microwave interference.
Sign Up to like & getrecommendations! Published in 2022 at "Optics express"
DOI: 10.1364/oe.459212
Abstract: High-precision spatial ranging plays a significant role in both scientific research and industrial practice. However, it is difficult for existing equipment to achieve high speed, high precision, and long distance simultaneously. Inspired by the concept… read more here.
Keywords: high precision; precision spatial; method high; spatial distance ... See more keywords
Concise method for high-precision vibration recovery of Φ-OTDR based on the GF-FastICA algorithm.
Sign Up to like & getrecommendations! Published in 2022 at "Optics letters"
DOI: 10.1364/ol.478931
Abstract: To efficiently restore the vibration signals of a phase-sensitive optical time domain reflectometer (Φ-OTDR), the GF-FastICA joint algorithm is proposed, which combines guided filtering with fast independent component analysis (FastICA). The marked region of vibration… read more here.
Keywords: high precision; method high; concise method; vibration ... See more keywords