A Robust HPLC Method for the Simultaneous Determination of Finerenone and Its Enantiomer Using AQbD.
Sign Up to like & getrecommendations! Published in 2025 at "Chirality"
DOI: 10.1002/chir.70052
Abstract: The enantiomeric purity of Finerenone (FIN), a novel therapeutic for chronic kidney disease (CKD), is a critical quality attribute for ensuring patient safety. This study reports the first chiral HPLC method for the simultaneous determination… read more here.
Keywords: enantiomer; method; hplc method; finerenone ... See more keywords
One‐step zymogram method for the simultaneous detection of cellulase/xylanase activity and molecular weight estimation of the enzyme
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600347
Abstract: Here, we describe a zymographic method for the simultaneous detection of enzymatic activity and molecular weight (MW) estimation, following a single electrophoresis step. This involved separating cellulase and xylanase activities from bacteria and fungi, obtained… read more here.
Keywords: estimation; cellulase xylanase; method simultaneous; cellulase ... See more keywords
A Semi‐Implicit Numerical Method for Simultaneous Fluid‐Structure Interaction
Sign Up to like & getrecommendations! Published in 2025 at "International Journal for Numerical Methods in Fluids"
DOI: 10.1002/fld.70019
Abstract: A one‐dimensional shallow water model is coupled with a floating boat which is assumed to be in hydrostatic equilibrium with the underlying water. Numerically, a semi‐implicit discretization of the shallow water equations also includes the… read more here.
Keywords: fluid structure; semi implicit; implicit numerical; simultaneous fluid ... See more keywords
UHPLC–MS/MS method for simultaneous quantification of doripenem, meropenem, ciprofloxacin, levofloxacin, pazufloxacin, linezolid, and tedizolid in filtrate during continuous renal replacement therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24815
Abstract: Since severe infections frequently cause acute kidney injury (AKI), continuous renal replacement therapy (CRRT) is often initiated for regulation of inflammatory mediators and renal support. Thus, it is necessary to decide the antibiotic dosage considering… read more here.
Keywords: method simultaneous; replacement therapy; simultaneous quantification; uhplc method ... See more keywords
A validated LC-MS/MS method for the simultaneous determination of 20-(S)-protopanaxatriol and its two active metabolites in rat plasma: Application to a pharmacokinetics study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700909
Abstract: We present a validated liquid chromatography with tandem mass spectrometry method for simultaneous determination of 20-(S)-protopanaxatriol and its two oxidative stereoisomeric metabolites (20S,24S)-epoxy-dammarane-3,6,12,25-tetraol (M1) and (20S,24R)-epoxy-dammarane-3,6,12,25-tetraol (M2) in rat plasma. 20-(S)-Protopanaxatriol, M1, and M2 were… read more here.
Keywords: simultaneous determination; rat plasma; protopanaxatriol two; method simultaneous ... See more keywords
An HPLC method for simultaneous quantification of metformin and ferulic acid in solid dosage forms.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200373
Abstract: Metformin is one of the most commonly used drugs in the world for the treatment of type 2 diabetes, while ferulic acid is a molecule that stands out for its antioxidant potential. Recent studies demonstrate… read more here.
Keywords: method simultaneous; simultaneous quantification; acid; hplc method ... See more keywords
A Highly Selective Stability-Indicating HPLC Method for Simultaneous Estimation of Sertaconazole with Two Coformulated Preservatives in Pharmaceutical Dosage Forms
Sign Up to like & getrecommendations! Published in 2019 at "Chromatographia"
DOI: 10.1007/s10337-019-03832-8
Abstract: Abstract The present investigation deals with the development of a validated stability-indicating HPLC–DAD method for the simultaneous determination of sertaconazole nitrate (SN) and two coformulated preservatives: sorbic acid (SA) and methylparaben (MP). The analytes were subjected to… read more here.
Keywords: stability indicating; method; indicating hplc; method simultaneous ... See more keywords
Development of a new method for simultaneous extraction of chlorophylls and carotenoids from microalgal biomass
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-021-02470-8
Abstract: There are still limitations in the pigment extraction methods used in microalgae biomass, especially for laboratory scale. This work aimed to develop a simple method for simultaneous extraction of chlorophylls and carotenoids from the microalgae… read more here.
Keywords: extraction chlorophylls; method; simultaneous extraction; extraction ... See more keywords
Development and Validation of a HPLC-HESI-MS/MS Method for Simultaneous Determination of Robenidine Hydrochloride and Its Metabolites in Fish and Exploration of Their Kinetic Regularities in Grass Carp
Sign Up to like & getrecommendations! Published in 2019 at "Food Analytical Methods"
DOI: 10.1007/s12161-019-01679-1
Abstract: An original method for the simultaneous determination of robenidine hydrochloride (ROBH) and its main metabolites 4-chlorohippuric acid (PCHA) and 4-chlorobenzoic acid (PCBA) in fish plasma and muscle was established by high-performance liquid chromatography coupled with… read more here.
Keywords: simultaneous determination; muscle; grass carp; method ... See more keywords
Development and validation of an RP-HPLC DAD method for the simultaneous quantification of minor and major whey proteins.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.128176
Abstract: Whey represents a valuable protein source for human nutrition. Whey composition varies with respect to process characteristics during milk processing. For efficient exploitation of this dairy side stream, reliable analytical methods are essential. The aim… read more here.
Keywords: dad method; method; method simultaneous; whey ... See more keywords
UPLC–MS/MS method for the simultaneous quantification of three new antiretroviral drugs, dolutegravir, elvitegravir and rilpivirine, and other thirteen antiretroviral agents plus cobicistat and ritonavir boosters in human plasma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.02.002
Abstract: &NA; Rilpivirine (RPV), dolutegravir (DTG) and elvitegravir (EVG) are the latest antiretroviral drugs approved for treatment of HIV infection. Currently, poor information is currently available concerning their pharmacokinetic and pharmacodynamic properties, thus making the use… read more here.
Keywords: uplc method; antiretroviral agents; method; antiretroviral drugs ... See more keywords