Method Validation Using Normal and Weighted Linear Regression Models for Quantification of Pesticides in Mango (Mangifera indica L.) Samples
Sign Up to like & getrecommendations! Published in 2018 at "Chromatographia"
DOI: 10.1007/s10337-018-3483-7
Abstract: A fast and efficient method was developed and validated for the determination of pesticides in mangos, which uses the QuEChERS citrate and gas chromatography–mass spectrometry (GC–MS) techniques. A detailed statistical analysis was performed to study… read more here.
Keywords: using normal; normal weighted; weighted linear; method validation ... See more keywords
Enzymatic method and its validation for the micromolar assay of glucose in human serum samples.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.113536
Abstract: This work depicts the novel chromogenic system for the assay of glucose in blood samples connected with the chelate formation of sulfosalicylic acid (SSA) with iron (Fe(III)) using glucose oxidase (GOD) presented. The purple-colored Fe-SSA… read more here.
Keywords: enzymatic method; method; serum; assay glucose ... See more keywords
LC–MS/MS method validation for the quantitation of 1-kestose in wheat flour
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Food Composition and Analysis"
DOI: 10.1016/j.jfca.2021.103930
Abstract: Abstract Fructan analysis is challenging due to several mono-, di-, and oligosaccharides as well as starch and proteins present in wheat grains which interfere with the analysis. So far, a sensitive and fully validated LC–MS/MS… read more here.
Keywords: quantitation kestose; wheat; method; method validation ... See more keywords
Design of Analytical Method Validation Protocol Evaluating Environmental Monitoring of AND Contamination on Surfaces Based on Cleaning Validation Procedures: A Multi Component RP-UHPLC Method.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmac071
Abstract: Environmental monitoring of anti-neoplastic drug (AND) residues in workplaces is crucial to limit exposure to workers who handle with them. Although wipe sampling is the most appropriate methodology to evaluate the risk, conflicting results are… read more here.
Keywords: method validation; validation; method; analytical method ... See more keywords
Cebranopadol, a novel first-in-class drug candidate: Method validation and first exploratory pharmacokinetic study in rabbits.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12948
Abstract: Cebranopadol is a novel, centrally acting, potent, first-in-class analgesic drug candidate with a unique mode of action that combines nociceptin/orphanin FQ peptide receptor and opioid peptide receptor agonism. The present study aimed to develop and… read more here.
Keywords: drug candidate; method; cebranopadol novel; method validation ... See more keywords
Method Validation and Characterization of Red Pigment in Beta vulgaris Peels and Pomaces by HPLC-UV and UHPLC-MS/MS
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Analytical Methods in Chemistry"
DOI: 10.1155/2022/2229500
Abstract: Color pigments from plant, animal, or mineral sources can be identified, separated, and quantified for various purposes. It is expected that pigments from Beta vulgaris L. peels and pomaces could be used to develop natural… read more here.
Keywords: method validation; beta vulgaris; hplc; vulgaris peels ... See more keywords
Replicates Number for Drug Stability Testing during Bioanalytical Method Validation—An Experimental and Retrospective Approach
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020457
Abstract: Background: The stability of a drug or metabolites in biological matrices is an essential part of bioanalytical method validation, but the justification of its sample size (replicates number) is insufficient. The international guidelines differ in… read more here.
Keywords: method validation; confidence intervals; bioanalytical method; stability ... See more keywords
Fusarium Mycotoxins in Maize Field Soils: Method Validation and Implications for Sampling Strategy
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14020130
Abstract: While mycotoxins are generally regarded as food contamination issues, there is growing interest in mycotoxins as environmental pollutants. The main sources of trichothecene and zearalenone mycotoxins in the environment are mainly attributed to Fusarium infested… read more here.
Keywords: method validation; validation; field soils; maize field ... See more keywords
Method Validation for Determination of Lignan Content in Fermented Sesame by Bioconversion
Sign Up to like & getrecommendations! Published in 2017 at "Journal of The Korean Society of Food Science and Nutrition"
DOI: 10.3746/jkfn.2017.46.5.646
Abstract: The aim of this study was to investigate method validation for determination of sesamol, sesamin, and sesamolin in non-fermented sesame and fermented sesame by bioconversion. For validation, the specificity, linearity, precision, accuracy, limits of detection… read more here.
Keywords: method validation; sesamin sesamolin; fermented sesame; validation determination ... See more keywords
Therapeutic drug monitoring of levetiracetam: Method validation using high-performance liquid chromatography-ultraviolet detector technique and usefulness in patient care setting
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Postgraduate Medicine"
DOI: 10.4103/jpgm.jpgm_467_21
Abstract: Objectives: To develop and validate a modified HPLC-UV method for the estimation of serum levetiracetam levels and to assess the usefulness of serum levetiracetam estimation in epileptic patients. Materials and Methods: Modification of a previously… read more here.
Keywords: method validation; levetiracetam levels; detector technique; levetiracetam ... See more keywords
European Bioanalysis Forum feedback on draft ICH M10 guideline on bioanalytical method validation during the Step 2b public consultation period.
Sign Up to like & getrecommendations! Published in 2020 at "Bioanalysis"
DOI: 10.4155/bio-2020-0065
Abstract: Once released, the ICH M10 Guideline on bioanalytical method validation will become one of the most important milestones in the history of regulated bioanalysis, closing a chapter on intense discussions among the industry and health… read more here.
Keywords: bioanalysis; bioanalytical method; guideline bioanalytical; method validation ... See more keywords