A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies
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DOI: 10.3389/fmolb.2022.886417
Abstract: Free-cysteine residues in recombinant biotherapeutics such as monoclonal antibodies can arise from incorrect cellular processing of disulfide bonds during synthesis or by reduction of disulfide bonds during the harvest and purification stage of manufacture. Free… read more here.
Keywords: free cysteine; methodologies detection; review methodologies; free cysteines ... See more keywords
Proteomics-Based Methodologies for the Detection and Quantification of Seafood Allergens
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DOI: 10.3390/foods9081134
Abstract: Seafood is considered one of the main food allergen sources by the European Food Safety Authority (EFSA). It comprises several distinct groups of edible aquatic animals, including fish and shellfish, such as crustacean and mollusks.… read more here.
Keywords: detection quantification; detection; quantification seafood; methodologies detection ... See more keywords