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Published in 2019 at "Methods in Molecular Biology"
DOI: 10.1007/978-1-4939-8955-3
Abstract: Drug repurposing is a creative and resourceful approach to increase the number of therapies by exploiting available and approved drugs. However, identifying new protein targets for previously approved drugs is challenging. Although new strategies have…
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Keywords:
protein;
drug repurposing;
methods drug;
drug ... See more keywords
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Published in 2020 at "Critical reviews in analytical chemistry"
DOI: 10.1080/10408347.2020.1857222
Abstract: Ezetimibe (EZM) is a selective inhibitor of the sterol transporter Niemann-Pick C1-Like 1 in the small intestine used as an adjunctive therapy to lower cholesterol levels in cases of hyperlipidemia. The goal of this work…
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Keywords:
review analytical;
analytical methods;
methods drug;
drug ... See more keywords
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Published in 2019 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2019/1526290
Abstract: Pre- and postmarket drug safety evaluations usually include an integrated summary of results obtained using data from multiple studies related to a drug of interest. This paper proposes three approaches based on the likelihood ratio…
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Keywords:
ratio test;
methods drug;
likelihood ratio;
drug ... See more keywords
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Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.00612
Abstract: Department of Pharmacy, University of Pisa, Pisa, Italy, 2 Laboratory of Molecular Modeling, Chemistry Department, Federal University of Lavras, Lavras, Brazil, Department of Chemistry, Faculty of Science, University of Hradec Kralove, Kralove, Czechia, DIFACQUIM Research…
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Keywords:
silico methods;
chemistry;
methods drug;
university ... See more keywords