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Methotrexate elicits pro-respiratory and anti-growth effects by promoting AMPK signaling

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0 Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-64460-z

Abstract: One-carbon metabolism fuels the high demand of cancer cells for nucleotides and other building blocks needed for increased proliferation. Although inhibitors of this pathway are widely used to treat many cancers, their global impact on… read more here.

Keywords: pro respiratory; elicits pro; methotrexate; ampk activation ... See more keywords