Association Between Low-Dose Methotrexate Exposure and Melanoma: A Systematic Review and Meta-analysis.
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DOI: 10.1001/jamadermatol.2022.3337
Abstract: Importance Methotrexate is widely used for the treatment of inflammatory disorders, including rheumatoid arthritis. Studies suggest that methotrexate may be associated with an increased risk of melanoma. Objective To determine whether methotrexate exposure is associated… read more here.
Keywords: melanoma; methotrexate; methotrexate exposure; risk ... See more keywords
Clinical outcomes of COVID-19 in patients taking tumor necrosis factor inhibitors or methotrexate: A multicenter research network study
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DOI: 10.1016/j.jaad.2020.09.009
Abstract: Background Data on the impact of biologics and immunomodulators on CoVid-19 related outcomes remains scarce. Objective To determine whether patients on tumor necrosis factor inhibitor (TNFi) and/or methotrexate are at increased risk of CoVid-19 related… read more here.
Keywords: methotrexate exposure; covid patients; methotrexate; tnfi methotrexate ... See more keywords
Optimum Methotrexate Exposure in Patients With Suspected or Confirmed CNS Invasive Hematological Malignancies: A Systematic Critical Review
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DOI: 10.1097/ftd.0000000000001022
Abstract: Background and Methods: The present review aims to evaluate the current state-of-the-art dosing regimens of high-dose (HD) and intrathecal methotrexate (MTX) using therapeutic drug monitoring (TDM) to optimize its therapeutic response and minimize associated toxicity,… read more here.
Keywords: optimum methotrexate; review; cns; methotrexate exposure ... See more keywords