Enhanced antitumor efficacy of poly(D,L-lactide-co-glycolide)-based methotrexate-loaded implants on sarcoma 180 tumor-bearing mice
Sign Up to like & getrecommendations! Published in 2017 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s143942
Abstract: Purpose Methotrexate is widely used in chemotherapy for a variety of malignancies. However, severe toxicity, poor pharmacokinetics, and narrow safety margin of methotrexate limit its clinical application. The aim of this study was to develop… read more here.
Keywords: tumor; methotrexate; sarcoma 180; loaded implants ... See more keywords
FORMULATION AND EVALUATION OF TOPICAL NANOEMULGEL OF METHOTREXATE FOR RHEUMATOID ARTHRITIS
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DOI: 10.22159/ijap.2021v13i5.41026
Abstract: Objective: The purpose of this study was to develop and evaluate methotrexate-loaded nanoemulgel for topical delivery in the management of rheumatoid arthritis. Methods: Based on nanoemulsion composition, the pseudo ternary phase diagram was fabricated by… read more here.
Keywords: nanoemulgel methotrexate; methotrexate; rheumatoid arthritis; methotrexate loaded ... See more keywords