N‐Substituted Nipecotic Acids as (S)‐SNAP‐5114 Analogues with Modified Lipophilic Domains
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DOI: 10.1002/cmdc.201900719
Abstract: Potential mGAT4 inhibitors derived from the lead substance (S)‐SNAP‐5114 have been synthesized and characterized for their inhibitory potency. Variations from the parent compound included the substitution of one of its aromatic 4‐methoxy and 4‐methoxyphenyl groups,… read more here.
Keywords: one aromatic; substituted nipecotic; aromatic methoxy; methoxy ... See more keywords
Bioreductive dynamic kinetic resolution of ethyl 2-methoxy-3-oxo-3-phenylpropanoate
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DOI: 10.1016/j.catcom.2019.105865
Abstract: Abstract Ketoreductase ChKRED12 from Chryseobacterium sp. CA49 was identified as a highly stereoselective catalyst for the bioreductive production of (2S,3S)-ethyl 3-hydroxy-2-methoxy-3-phenylpropanoate (EMHP) through dynamic kinetic resolution. Its performance was further improved using semi-rational design strategies… read more here.
Keywords: bioreductive dynamic; ethyl; kinetic resolution; methoxy ... See more keywords
NLOphoric multichromophoric auxiliary methoxy aided triphenylamine D-π-A chromophores – Spectroscopic and computational studies
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DOI: 10.1016/j.optmat.2017.09.017
Abstract: Abstract Molecules containing methoxy supported triphenylamine as strong electron-donor and dicyanovinyl as electron-acceptor groups interacting via isophorone as a configurationally locked polyene π-conjugated bridge are studied for their nonlinear optical properties. The photophysical study of… read more here.
Keywords: auxiliary methoxy; methoxy; nlophoric multichromophoric; multichromophoric auxiliary ... See more keywords
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities.
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DOI: 10.1016/j.phytochem.2021.112656
Abstract: Three previously undescribed pyridyl-steroidal glycoalkaloids, solanindiosides A‒C, one rare 23S,26R-hydroxylated spirostanoid saponin, and two steroidal alkaloid aglycones, solanindins A and B, derived from the acid hydrolysis of solanindiosides A‒C, were isolated from the fruits of… read more here.
Keywords: hydroxy methoxyphenyl; pyridyl steroidal; undescribed pyridyl; methoxy ... See more keywords
A new resorcinol derivative from the bark of Aegiceras floridum (Primulaceae).
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DOI: 10.1080/14786419.2020.1855163
Abstract: Chemical investigation of the Vietnamese plant Aegiceras floridum Roem. & Schult. (Primulaceae) led to the isolation of the new compound 3-methoxy-5-nonylphenol (1) along with five known ones 2,8,10-trihydroxy-6H-benzo[c]chromen-6-one (2), 2-hydroxy-5-methoxy-3-nonylbenzo-1,4-quinone (3), 5-(3-hydroxypropyl)-7-methoxy-3-(methylbenzofuran-2-yl)-3-methoxyphenol (4), 2,8-dihydroxy-7-methoxy-3,9-diundecyldibenzofuran-1,4-dione (5)… read more here.
Keywords: derivative bark; resorcinol derivative; new resorcinol; methoxy ... See more keywords