Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
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DOI: 10.1016/j.bioorg.2021.104919
Abstract: Many clinically used agents active in cancer chemotherapy exert their activity through the induction of cell death (apoptosis) by targeting microtubules, altering protein function or inhibiting DNA synthesis. The benzo[b]thiophene scaffold holds a pivotal place… read more here.
Keywords: apoptosis; thiophene; methoxybenzo; aryl ... See more keywords