Articles with "methoxyphenyl nitrophenyl" as a keyword



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Synthesis, biological evaluation and molecular docking study of N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide derivatives as potent HIV-1 Vif antagonists.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.01.010

Abstract: Viral infectivity factor (Vif) is protective against APOBEC3G (A3G)-mediated viral cDNA hypermutations, and development of molecules that inhibit Vif mediated A3G degradation is a novel strategy for blocking HIV-1 replication. Through optimizations of the central… read more here.

Keywords: methoxyphenyl nitrophenyl; benzamide; biological evaluation; molecular docking ... See more keywords