Negative allosteric modulators of NMDA receptors with GluN2B subunit: Alanine‐derived benzoxazolone bioisosteres of 2‐methyl‐3‐benzazepine‐1,7‐diols
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200177
Abstract: Inspired by besonprodil, the phenol of potent negative allosteric modulators of GluN2B‐N‐methyl‐d‐aspartate (NMDA) receptors was replaced by a benzoxazolone system. To increase the similarity to the lead compounds, an additional methyl moiety was installed in… read more here.
Keywords: nmda receptors; allosteric modulators; moiety; benzoxazolone ... See more keywords
FRET‐Based In‐Cell Detection of Highly Selective Supramolecular Complexes of meso‐Tetraarylporphyrin with Peptide/BODIPY‐Modified Per‐O‐Methyl‐β‐Cyclodextrins
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100380
Abstract: Artificial supramolecular systems capable of self‐assembly and that precisely function in biological media are in high demand. Herein, we demonstrate a highly specific host‐guest‐pair system that functions in living cells. A per‐O‐methyl‐β‐cyclodextrin derivative (R8‐B‐CDMe) bearing… read more here.
Keywords: methyl; peptide; living cells; per methyl ... See more keywords
Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid
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DOI: 10.1002/cmdc.201600626
Abstract: A total of 41 new triterpenoids were prepared from allobetulone, methyl betulonate, methyl oleanonate, and oleanonic acid to study their influence on cancer cells. Each 3‐oxotriterpene was brominated at C2 and substituted with thiocyanate; subsequent… read more here.
Keywords: methyl; betulonate methyl; cytotoxic; methyl betulonate ... See more keywords
Aryl Methyl Sulfone Construction from Eco-Friendly Inorganic Sulfur Dioxide and Methyl Reagents.
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DOI: 10.1002/cssc.201802919
Abstract: A three-component cross-coupling protocol of boronic acid, sodium metabisulfite, and dimethyl carbonate was developed for the construction of significant functional methyl sulfones, in which introduction of sulfur dioxide at the last stage was successfully achieved… read more here.
Keywords: eco friendly; methyl; construction; sulfur dioxide ... See more keywords
Impurity profiling of methamphetamine synthesized from methyl α-acetylphenylacetate (MAPA).
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3256
Abstract: The group of P2P precursors including α-phenylacetoacetonitrile (APAAN), α-phenylacetoamide (APAA) and methyl α-acetylphenylacetate (MAPA) have become increasingly popular in Europe and other parts of the world in the last decade. Previous investigations have reported the… read more here.
Keywords: methyl acetylphenylacetate; methamphetamine synthesized; methamphetamine; acetylphenylacetate mapa ... See more keywords
Methyl chitosan coating for glycoform analysis of glycoproteins by capillary electrophoresis
Sign Up to like & getrecommendations! Published in 2020 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201900333
Abstract: CE is a promising technique for the analysis of glycosylated proteins, especially at the intact level. In the present study, the utility of CE for the separation of protein glycoforms is developed by using methyl… read more here.
Keywords: methyl; glycoform analysis; methyl chitosan;
A facile noncatalytic methyl ester production from waste chicken tallow using single step subcritical methanol: Optimization study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Energy Research"
DOI: 10.1002/er.4844
Abstract: In this modern era, an increase in urbanization causes the escalating trend of fuel demand as well as environmental pollution problems. Various biofuels research with the respect of climate change and emission reduction recently intensifies,… read more here.
Keywords: chicken tallow; waste; study; methyl ... See more keywords
Uptake and Effects of Nanoplastics on the Dinoflagellate Gymnodinium corollarium
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5604
Abstract: Plastic nanoparticles (NPs) are the final state of plastic degradation in the environment before they disintegrate into low‐molecular‐weight organic compounds. Unicellular organisms are highly sensitive to the toxic effects of nanoplastics, because they are often… read more here.
Keywords: effects nanoplastics; dinoflagellate gymnodinium; plastic; gymnodinium corollarium ... See more keywords
Identification of an unusual by-product in the industrial production of 2-Methyl-3-furanthiol
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DOI: 10.1002/ffj.3409
Abstract: A by-product provided by the producer of 2-methyl-3-furanthiol was characterized by 1D and 2D NMR, GC–MS (EI) and HRMS analyses. It was identified to be 4-(5-methyl-2-furylthio)-5-methyltetrahydrofuran-2-thione and its precursor 2-methyl-5-thioacetylfuran was also determined. 2-Methyl-5-thioacetylfuran was… read more here.
Keywords: methyl; industrial production; product; production methyl ... See more keywords
Multi-factorial investigation of the effect of biochar of the secondary medicinal residue of snow lotus on the adsorption of two azo dyes, methyl red and methyl orange.
Sign Up to like & getrecommendations! Published in 2023 at "Microscopy research and technique"
DOI: 10.1002/jemt.24343
Abstract: Azo dye residues pollute water, which are difficult to decompose, and posing a major threat to the ecological environment. The residues of Chinese medicine still have many possibilities for use after its medicinal value has… read more here.
Keywords: adsorption; spectroscopy; microscopy; snow lotus ... See more keywords
Maintaining postharvest quality of cold stored 'Hass' avocados by altering the fatty acids content and composition with the use of natural volatile compounds - methyl jasmonate and methyl salicylate.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8400
Abstract: BACKGROUND Low temperatures are often used to reduce metabolic processes and extend the storage life of fruit; however, in the case of avocado, a temperature below 3 °C will often result in the development of physiological… read more here.
Keywords: methyl; methyl jasmonate; methyl salicylate; chilling injury ... See more keywords