Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARĪ³ agonists.
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DOI: 10.1016/j.ejmech.2016.11.051
Abstract: In this structure-activity relationship study, the influence of aryl substituents at position 5 or 6 on the pharmacological profile of the partial PPARĪ³ agonist 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid was investigated. This lead was previously identified as the… read more here.
Keywords: ppar; pharmacological profile; benzo imidazol; imidazol methyl ... See more keywords