The Ultrafast Dynamics of the Two Lowest Bright Excited States of Cytosine and 1-Methyl-Cytosine: A Quantum Dynamical Study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.0c00455
Abstract: The nonadiabatic quantum dynamics (QD) of cytosine and 1-methyl-cytosine in gas phase is simualted for 250 fs after a photoexcitation to oneof the first two bright states is simulated. The nuclear wavepacket is propa-gated on… read more here.
Keywords: state; quantum; cytosine methyl; excited states ... See more keywords
5-Methyl-cytosine stabilizes DNA but hinders DNA hybridization revealed by magnetic tweezers and simulations
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1122
Abstract: Abstract 5-Methyl-cytosine (5mC) is one of the most important DNA modifications and plays versatile biological roles. It is well known that 5mC stabilizes DNA duplexes. However, it remains unclear how 5mC affects the kinetics of… read more here.
Keywords: methyl cytosine; stabilizes dna; dna hybridization; hybridization ... See more keywords
Ten-eleven translocation methyl-cytosine dioxygenase 2 deficiency exacerbates renal ischemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Epigenetics"
DOI: 10.1186/s13148-020-00892-8
Abstract: Background Ten-eleven translocation (Tet) methyl-cytosine dioxygenases (including Tet1/2/3)-mediated 5mC oxidation and DNA demethylation play important roles in embryonic development and adult tissue homeostasis. The expression of Tet2 and Tet3 genes are relatively abundant in the… read more here.
Keywords: renal ischemia; ten eleven; eleven translocation; injury ... See more keywords