Methyl Scanning for Mechanochemical Chalcogen‐Bonding Cascade Switches
Sign Up to like & getrecommendations! Published in 2020 at "ChemistryOpen"
DOI: 10.1002/open.201900288
Abstract: Abstract Chalcogen‐bonding cascade switching was introduced recently to produce the chemistry tools needed to image physical forces in biological systems. In the original flipper probe, one methyl group appeared to possibly interfere with the cascade… read more here.
Keywords: bonding cascade; chalcogen bonding; methyl group;
Validation of a food-frequency questionnaire to assess methyl-group donor intake in preschoolers
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-021-04367-7
Abstract: A good assessment of dietary methyl-group donor intake (folate, choline, betaine, methionine) is needed to investigate the effect of methyl-group donor intake on children’s health. The aim is to develop and validate a food-frequency questionnaire… read more here.
Keywords: methyl group; group; food frequency; frequency questionnaire ... See more keywords
The 1-β-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.01.082
Abstract: L,D-transpeptidases, widely distributed in bacteria and even in the difficult-to-treat ESKAPE pathogens, can confer antibacterial resistance against the traditional β-lactam antibiotics through bypass of the 4 → 3 transpeptide linkage. LdtMt2, a l,d-transpeptidase in Mycobacteria tuberculosis, is… read more here.
Keywords: transpeptidase; ertapenem; affinity; methyl group ... See more keywords
The two-top molecule 3-penten-2-one: Acetyl methyl torsion in α,β-unsaturated ketones
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131337
Abstract: Abstract Using a molecular jet Fourier transform spectrometer, the microwave spectrum of E-3-penten-2-one, also called methyl propenyl ketone, was recorded in a range from 2.0 to 26.5 GHz. Two conformers, antiperiplanar (ap) and synperiplanar (sp), could… read more here.
Keywords: penten one; acetyl methyl; unsaturated ketones; methyl ... See more keywords
Recent advances of the site-specific direct methylation on aromatic rings
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132402
Abstract: Abstract Five- and six-membered aromatic rings bearing a methyl group are important molecular fragments in drug discovery. From the medicinal chemistry standpoint, the methyl group might play a pivotal role in improving the biological activities… read more here.
Keywords: recent advances; direct methylation; methyl group; aromatic rings ... See more keywords
Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2020.11.015
Abstract: Meloxicam is a thiazole-containing NSAID that was approved for marketing with favorable clinical outcomes despite being structurally similar to the hepatotoxic sudoxicam. Introduction of a single methyl group on the thiazole results in an overall… read more here.
Keywords: sudoxicam; methyl group; group; bioactivation ... See more keywords
Mass Transfer Advantage of Hierarchical Zeolites Promotes Methanol Converting into para-Methyl Group in Toluene Methylation
Sign Up to like & getrecommendations! Published in 2017 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.7b02187
Abstract: Investigating the mass transfer of toluene methylation with methanol will contribute to converting more methanol feedstock into the para-methyl group. The reaction system was considered as three competing reactions: toluene methylation and isomerization of para-xylene… read more here.
Keywords: methylation; mass transfer; toluene methylation; methyl group ... See more keywords
Iridium-Catalyzed C-Alkylation of Methyl Group on N-Heteroaromatic Compounds using Alcohols.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02635
Abstract: In this study, we developed a catalytic system for the C-alkylation of a methyl group on N-heteroaromatic compounds, including pyridine, pyrimidine, pyrazine, quinoline, quinoxaline, and isoquinoline, using alcohols based on a hydrogen-borrowing process with [Cp*IrCl2]2… read more here.
Keywords: group heteroaromatic; methyl group; heteroaromatic compounds; alkylation methyl ... See more keywords
Biosynthesis of the Sesquiterpene Kitaviridene through Skeletal Rearrangement with Formation of a Methyl Group Equivalent.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01211
Abstract: A sesquiterpene synthase from Kitasatospora viridis was discovered and shown to produce kitaviridene, a sesquiterpene hydrocarbon with an additional methyl group equivalent in comparison to a regular sesquiterpene. Isotopic labeling experiments together with DFT calculations… read more here.
Keywords: kitaviridene; sesquiterpene; group equivalent; formation ... See more keywords
Diversity of methyl group dynamics in felodipine: a DFT supported NMR and QENS study
Sign Up to like & getrecommendations! Published in 2018 at "CrystEngComm"
DOI: 10.1039/c8ce01605d
Abstract: Molecular and vibrational dynamics in a widely used calcium channel blocker, felodipine form I (FLD), have been thoroughly explored by combining periodic density functional theory (plane-wave DFT) with solid-state nuclear magnetic resonance (NMR), high-resolution quasielastic… read more here.
Keywords: dft; methyl group; diversity methyl; group dynamics ... See more keywords
Three ligand-originated MOF isomers: the positional effect of the methyl group on structures and selective C2H2/CH4 and CO2/CH4 adsorption properties.
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt01017j
Abstract: Three copper-based ligand-originated MOF isomers (ZJNU-81, ZJNU-82 and ZJNU-83) derived from methyl-functionalized V-shaped diisophthalate ligands were solvothermally synthesized and structurally characterized. Single-crystal X-ray diffraction studies revealed that the position of the methyl group in the… read more here.
Keywords: adsorption; adsorption properties; methyl group; ch4 ... See more keywords