Nucleophilic substitution reactions of 1-methyl-4,5-dinitroimidazole with aqueous ammonia or sodium azide
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DOI: 10.1007/s10593-018-2389-5
Abstract: In this work, 5-amino-1-methyl-4-nitroimidazole was synthesized by amination reaction of 1-methyl-4,5-dinitroimidazole with aqueous ammonia in 95% yield. Meanwhile, one of its isomers, 4-amino-1-methyl-5-nitroimidazole as byproduct was obtained from the filtrate. Furthermore, nucleophilic substitution reaction of… read more here.
Keywords: methyl dinitroimidazole; dinitroimidazole aqueous; nucleophilic substitution; aqueous ammonia ... See more keywords