iDNA6mA (5-step rule): Identification of DNA N6-methyladenine sites in the rice genome by intelligent computational model via Chou's 5-step rule
Sign Up to like & getrecommendations! Published in 2019 at "Chemometrics and Intelligent Laboratory Systems"
DOI: 10.1016/j.chemolab.2019.04.007
Abstract: Abstract DNA methylation is an elementary epigenetic process. The N6-methyladenine is related to a large kind of biological processes i.e., transcription, DNA replication, and repair. In genome, the N6-methyladenine (6 mA) site distribution is non-random; therefore,… read more here.
Keywords: step rule; model; methyladenine; computational model ... See more keywords
Artificially Evolved Superbinder for Specific Recognition of N6-Methyladenine Base Modification in DNA and RNA.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00588
Abstract: N6-Methyladenine (m6A/6mA) is a functional epigenetic base modification found in RNA and DNA. By selecting one RNA m6A reader as a template, we created a series of libraries of 3 × 108 RNA m6A reader… read more here.
Keywords: methyladenine; base modification; dna; rna ... See more keywords
N6-methyladenine in DNA antagonizes SATB1 in early development
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DOI: 10.1038/s41586-020-2500-9
Abstract: The recent discovery of N6-methyladenine (N6-mA) in mammalian genomes suggests that it may serve as an epigenetic regulatory mechanism1. However, the biological role of N6-mA and the molecular pathways that exert its function remain unclear.… read more here.
Keywords: early development; methyladenine; dna; chromatin ... See more keywords
Cell Death Triggered by the Autophagy Inhibitory Drug 3-Methyladenine in Growing Conditions Proceeds With DNA Damage
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.580343
Abstract: Macroautophagy (hereafter autophagy) is a multistep intracellular catabolic process with pleiotropic implications in cell fate. Attending to its activation, autophagy can be classified into inducible or constitutive. Constitutive, or basal autophagy, unfolds under nutrient-replete conditions… read more here.
Keywords: dna damage; methyladenine; cell death; cell ... See more keywords