N6-methyladenosine modification of CENPF mRNA facilitates gastric cancer metastasis via regulating FAK nuclear export.
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DOI: 10.1002/cac2.12443
Abstract: BACKGROUND N6-methyladenosine (m6 A) modification is the most common modification that occurs in eukaryotes. Although substantial effort has been made in the prevention and treatment of gastric cancer (GC) in recent years, the prognosis of… read more here.
Keywords: metastasis; modification; cenpf; modification cenpf ... See more keywords
RNA N 6-Methyladenosine Modification in Normal and Malignant Hematopoiesis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-7342-8_4
Abstract: As the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), N 6-methyladenosine (m6A) modification has been shown recently to posttranscriptionally regulate expression of thousands of messenger RNA (mRNA) transcripts in each mammalian cell type… read more here.
Keywords: hematopoiesis; m6a modification; rna methyladenosine; methyladenosine modification ... See more keywords
Functions of RNA N6-methyladenosine modification in cancer progression
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DOI: 10.1007/s11033-019-04655-4
Abstract: N6-methyladenosine (m6A) serves as a major RNA methylation modification and impacts the initiation and progression of various human cancers through diverse mechanisms. It has been reported that m6A RNA methylation is involved in different physiological… read more here.
Keywords: rna methyladenosine; methyladenosine modification; functions rna; progression ... See more keywords
Effects of N6-Methyladenosine Modification on Cancer Progression: Molecular Mechanisms and Cancer Therapy
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DOI: 10.3389/fonc.2022.897895
Abstract: N6-methyladenosine (m6A) is a major internal epigenetic modification in eukaryotic mRNA, which is dynamic and reversible. m6A is regulated by methylases (“writers”) and demethylases (“erasers”) and is recognized and processed by m6A-binding proteins (“readers”), which… read more here.
Keywords: effects methyladenosine; modification cancer; methyladenosine modification; m6a ... See more keywords
N6-methyladenosine Modification of Noncoding RNAs: Mechanisms and Clinical Applications in Cancer
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DOI: 10.3390/diagnostics12122996
Abstract: N6-methyladenosine (m6A) modification remains the most pivotal epigenetic modification on RNA. As we know, m6A not only affects physiological processes but is also involved in carcinoma. Noncoding RNAs play an indispensable role in the occurrence… read more here.
Keywords: modification noncoding; modification; clinical applications; noncoding rnas ... See more keywords