Articles with "methyladenosine rna" as a keyword



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N6-Methyladenosine RNA Modification in Inflammation: Roles, Mechanisms, and Applications

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.670711

Abstract: N6-methyladenosine (m6A) is the most prevalent internal mRNA modification. m6A can be installed by the methyltransferase complex and removed by demethylases, which are involved in regulating post-transcriptional expression of target genes. RNA methylation is linked… read more here.

Keywords: inflammation roles; rna modification; modification inflammation; methyladenosine rna ... See more keywords
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Contributions and Prognostic Values of N6-Methyladenosine RNA Methylation Regulators in Hepatocellular Carcinoma

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Published in 2020 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2020.614566

Abstract: Introduction The methylation at position N6 of adenine is called N6-methyladenosine (m6A). This transcriptional RNA modification exerts a very active and important role in RNA metabolism and in other biological processes. However, the activities of… read more here.

Keywords: hepatocellular carcinoma; methylation; methylation regulators; methyladenosine rna ... See more keywords
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N6-Methyladenosine RNA-Binding Protein YTHDF1 in Gastrointestinal Cancers: Function, Molecular Mechanism and Clinical Implication

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14143489

Abstract: Simple Summary N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in the occurrence and development of diseases. YTHDF1 is the most powerful and abundant m6A-encoded RNA reader.… read more here.

Keywords: gastrointestinal cancers; function molecular; ythdf1; m6a ... See more keywords