Determination of nucleobase-pairing free energies from rotamer equilibria of 2-(methylamino)pyrimidines.
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DOI: 10.1039/c9cc05513d
Abstract: A fast straightforward method for the determination of free energies of modified nucleobase pairing is proposed. The method is based on the nuclear magnetic resonance (NMR) spectroscopy monitoring of conformational changes of 2-(methylamino)-pyrimidines upon intermolecular… read more here.
Keywords: pairing free; methylamino pyrimidines; free energies; determination nucleobase ... See more keywords