Accounting for differential variability in detecting differentially methylated regions
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbx097
Abstract: Abstract DNA methylation plays an essential role in cancer. Differential variability (DV) in cancer was recently observed that contributes to cancer heterogeneity and has been shown to be crucial in detecting epigenetic field defects, DNA… read more here.
Keywords: methylation; differential variability; new method; differentially methylated ... See more keywords
DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data
Sign Up to like & getrecommendations! Published in 2017 at "BMC Bioinformatics"
DOI: 10.1186/s12859-017-1909-0
Abstract: BackgroundDNA methylation is an epigenetic modification that is studied at a single-base resolution with bisulfite treatment followed by high-throughput sequencing. After alignment of the sequence reads to a reference genome, methylation counts are analyzed to… read more here.
Keywords: methylation; identifying differentially; dmrfinder; differentially methylated ... See more keywords
Detection of differentially methylated regions of irradiated fig tree selections
Sign Up to like & getrecommendations! Published in 2017 at "Scientia Agricola"
DOI: 10.1590/1678-992x-2016-0195
Abstract: Fig tree (Ficus carica L.) breeding programs using conventional methods, such as directed crosses, to obtain new cultivars, are unworkable in many countries, including Brazil. Consequently, genetic breeding through mutagenesis has emerged as an important… read more here.
Keywords: fig tree; irradiated fig; dna; differentially methylated ... See more keywords
Differentially methylated regions identified in bovine embryos are not observed in adulthood
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DOI: 10.1590/1984-3143-ar2022-0076
Abstract: Abstract The establishment of epigenetic marks during the reprogramming window is susceptible to environmental influences, and stimuli during this critical stage can cause altered DNA methylation in offspring. In a previous study, we found that… read more here.
Keywords: methylation; adulthood; methylated regions; differentially methylated ... See more keywords
Obesity-Associated Differentially Methylated Regions in Colon Cancer
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DOI: 10.3390/jpm12050660
Abstract: Obesity with adiposity is a common disorder in modern days, influenced by environmental factors such as eating and lifestyle habits and affecting the epigenetics of adipose-based gene regulations and metabolic pathways in colorectal cancer (CRC).… read more here.
Keywords: colon cancer; methylated regions; obesity; differentially methylated ... See more keywords