Retrotransposon methylation and activity in wild fish (A. anguilla): A matter of size.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.11.014
Abstract: Understanding how organisms cope with global change is a major question in many fields of biology. Mainly, understanding the molecular mechanisms supporting rapid phenotypic changes of organisms in response to stress and linking stress-induced molecular… read more here.
Keywords: wild fish; methylation; methylation activity; retrotransposon methylation ... See more keywords
Tetramerization at low pH licenses DNA methylation activity of M.HpyAXI in the presence of acid stress.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.10.001
Abstract: Methylation of genomic DNA can influence the transcription profile of an organism and may generate phenotypic diversity for rapid adaptation in a dynamic environment. M.HpyAXI is a type III DNA methyltransferase present in Helicobacter pylori… read more here.
Keywords: methylation; methylation activity; dna; hpyaxi ... See more keywords
Loss-of-function and missense variants in NSD2 cause decreased methylation activity and are associated with a distinct developmental phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Genetics in Medicine"
DOI: 10.1038/s41436-021-01158-1
Abstract: Purpose Despite a few recent reports of patients harboring truncating variants in NSD2, a gene considered critical for the Wolf–Hirschhorn syndrome (WHS) phenotype, the clinical spectrum associated with NSD2 pathogenic variants remains poorly understood. Methods… read more here.
Keywords: phenotype; missense variants; methylation activity;