DNA methylation age as a biomarker for cancer
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Cancer"
DOI: 10.1002/ijc.33451
Abstract: Cancer is well established as an age‐associated disease, and there is substantial overlap in the molecular, cellular and physiological changes observed with both ageing and the progression of cancer. Age‐specific declines in resilience mechanisms such… read more here.
Keywords: cancer; age; dna methylation; methylation age ... See more keywords
SA8 ACCELERATED EPIGENETIC AGEING ASSOCIATED WITH MAJOR DEPRESSIVE DISORDER, NEUROTICISM, AND PSYCHOLOGICAL DISTRESS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.080
Abstract: Background Major Depression (MDD), neuroticism and psychological distress have each been associated with an increased risk of several diseases commonly associated with ageing. In the current study, we sought to identify which of these traits… read more here.
Keywords: methylation age; neuroticism psychological; distress; psychological distress ... See more keywords
Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume
Sign Up to like & getrecommendations! Published in 2017 at "Translational Psychiatry"
DOI: 10.1038/tp.2017.188
Abstract: Numerous studies have linked exposure to stress to adverse health outcomes through the effects of cortisol, a product of the stress response system, on cellular aging processes. Accelerated DNA methylation age is a promising epigenetic… read more here.
Keywords: methylation age; age; hippocampal volume; accelerated dna ... See more keywords
A Clinical Trial Using Methylation Age to Evaluate Current Antiaging Practices.
Sign Up to like & getrecommendations! Published in 2019 at "Rejuvenation research"
DOI: 10.1089/rej.2018.2083
Abstract: Recent advances in the technology of "aging clocks" based on DNA methylation suggest that it may be possible to measure changes in the rate of human aging over periods as short as a year or… read more here.
Keywords: clinical trial; methylation; methylation age; trial using ... See more keywords
The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Epigenetics"
DOI: 10.1186/s13148-019-0656-7
Abstract: BackgroundAgeing is one of the principal risk factors for many chronic diseases. However, there is considerable between-person variation in the rate of ageing and individual differences in their susceptibility to disease and death. Epigenetic mechanisms… read more here.
Keywords: risk; methylation age; age; disease ... See more keywords