DNA methylation alterations in muscle of critically ill patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12970
Abstract: Intensive care unit (ICU)‐acquired weakness can persist beyond ICU stay and has been associated with long‐term functional impairment of ICU survivors. Recently, DNA methylation alterations were found in the blood of ICU patients, partially explaining… read more here.
Keywords: ill patients; long term; methylation; critically ill ... See more keywords
Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy
Sign Up to like & getrecommendations! Published in 2023 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddad016
Abstract: Abstract Berardinelli–Seip congenital lipodystrophy type 2 (CGL2) is a very rare human genetic disorder with potential significance to the understanding of the pathobiology of aging. CGL2 patients display characteristic progeroid features and suffer from type… read more here.
Keywords: dna; cgl2 patients; methylation alterations; dna methylation ... See more keywords
Clustered protocadherins methylation alterations in cancer
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Epigenetics"
DOI: 10.1186/s13148-019-0695-0
Abstract: BackgroundClustered protocadherins (PCDHs) map in tandem at human chromosome 5q31 and comprise three multi-genes clusters: α-, β- and γ-PCDH. The expression of this cluster consists of a complex mechanism involving DNA hub formation through DNA-CCTC… read more here.
Keywords: methylation; cpg islands; methylation alterations; cancer clustered ... See more keywords